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Figure 6 | Lipids in Health and Disease

Figure 6

From: Different responses to oxidized low-density lipoproteins in human polarized macrophages

Figure 6

Quantitative real-time RT-PCR. A. IL8 mRNA expression levels. The expression level of IL8 was significantly upregulated by oxLDL treatment in M1 macrophages (P < 0.05). IL8 expression level after oxLDL treatment in M2 was markedly lower than those in M0 and M1 macrophages (P < 0.05). B. HMOX1 mRNA expression levels. OxLDL treatment significantly enhanced HMOX1 gene expression by 7.6-fold (**P < 0.0005), 5.8-fold (*P < 0.05), and 5.9-fold (*P < 0.05) in M0, M1, and M2 macrophages, respectively. HMOX1 gene expression levels were almost the same in all 3 subsets of macrophages even after oxLDL treatment. Each bar shows the mean ± SD of 3 experiments.

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