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Table 2 Effects of simvastatin on serum lipid levels (mmol/L)

From: Effects of simvastatin on apolipoprotein M in vivo and in vitro

Groups

N

TC

TG

HDL-C

LDL-C

Normal control

6

2.39 ± 0.17

2.30 ± 0.26

0.27 ± 0.03

0.26 ± 0.02

Vehicle control

9

3.59 ± 0.22a

1.58 ± 0.11b

1.17 ± 0.10b

0.73 ± 0.06b

Simvastatin (10 mg/kg)

10

3.84 ± 0.18

1.19 ± 0.08

1.34 ± 0.12

0.76 ± 0.04

Simvastatin (100 mg/kg)

14

4.49 ± 0.25*

1.33 ± 0.09

1.59 ± 0.17

0.93 ± 0.09

  1. Data are shown as means ± SEM. TC (total cholesterol), HDL-C (high density lipoprotein cholesterol), LDL-C (low density lipoprotein cholesterol), TG (triglyceride). *P < 0.05 vs. vehicle control, aP < 0.05 vs. normal control, bP < 0.01 vs. normal control.
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Lipids in Health and Disease

ISSN: 1476-511X