Can apricot kernels fatty acids delay the atrophied hepatocytes from progression to fibrosis in dimethylnitrosamine (DMN)-induced liver injury in rats?

Table 4 Effect of different levels of GAK on liver functions in serum with DMN induced hepatic fibrosis in rats ( n = 9)

Rat groups	AST (IU/mL)	ALT (IU/mL)	MDA (μmol)
I	85 ± 2.1^a	243 ± 2.6^a	2.30 ± 2.8^a
II	451.2 ± 2.3^b	582 ± 8.3^b	2.97 ± 2.3^b
III	261 ± 2.8^c	446 ± 2.7^c	2.48 ± 1.5^c
IV	224 ± 2.4^d	312 ± 2.9^d	2.53 ± 3.1^c
V	217 ± 4.7^d	289 ± 4.1^d	2.29 ± 2.1^a

Group I: fed on basal diet as a negative control group (NC). Group II: injected with DMN and fed on basal, used as a positive control group (PC). Group III: injected with DMN and fed on basal diet containing (ground apricot kernel) in amount of 0.5 mg/kg of body weigh/rat. Group IV: injected with DMN and fed on basal diet containing (ground apricot kernel) in amount of 1 mg/kg of body weigh/rat Group V: injected with DMN and fed on basal diet containing (ground apricot kernel) in amount of 1.5 mg/kg of body weigh/rat Values which don't share the same letter in each column are significantly different. Significance at P < 0.05 (± SD).

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