Skip to main content

Advertisement

Table 4 Effect of different levels of GAK on liver functions in serum with DMN induced hepatic fibrosis in rats ( n = 9)

From: Can apricot kernels fatty acids delay the atrophied hepatocytes from progression to fibrosis in dimethylnitrosamine (DMN)-induced liver injury in rats?

Rat groups AST (IU/mL) ALT (IU/mL) MDA (μmol)
I 85 ± 2.1a 243 ± 2.6a 2.30 ± 2.8a
II 451.2 ± 2.3b 582 ± 8.3b 2.97 ± 2.3b
III 261 ± 2.8c 446 ± 2.7c 2.48 ± 1.5c
IV 224 ± 2.4d 312 ± 2.9d 2.53 ± 3.1c
V 217 ± 4.7d 289 ± 4.1d 2.29 ± 2.1a
  1. Group I: fed on basal diet as a negative control group (NC). Group II: injected with DMN and fed on basal, used as a positive control group (PC). Group III: injected with DMN and fed on basal diet containing (ground apricot kernel) in amount of 0.5 mg/kg of body weigh/rat. Group IV: injected with DMN and fed on basal diet containing (ground apricot kernel) in amount of 1 mg/kg of body weigh/rat Group V: injected with DMN and fed on basal diet containing (ground apricot kernel) in amount of 1.5 mg/kg of body weigh/rat Values which don't share the same letter in each column are significantly different. Significance at P < 0.05 (± SD).