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Table 2 Renal function in Chinese Bama minipigs

From: Preventive effect of Ibrolipim on suppressing lipid accumulation and increasing lipoprotein lipase in the kidneys of diet-induced diabetic minipigs

Parameters

Baseline

2 months

4 months

5 months

Urinary microalbumin/creatinine ratio (mg/g)

   CD

12.26 ± 2.54

12.77 ± 3.33

13.52 ± 4.67

12.60 ± 3.27

   HSFD

12.73 ± 3.14

14.16 ± 3.53

25.13 ± 4.65 *

48.08 ± 11.77 **

   HSFD+Ibrolipim

13.18 ± 3.45

12.66 ± 4.01

17.24 ± 5.63 #

24.14 ± 7.99 ##

Plasma creatinine (μmol/l)

   CD

28.56 ± 5.54

28.97 ± 7.44

28.81 ± 6.02

29.69 ± 3.81

   HSFD

26.67 ± 6.53

27.71 ± 6.36

30.76 ± 8.91

33.38 ± 9.10

   HSFD+Ibrolipim

28.77 ± 7.34

30.25 ± 6.17

31.56 ± 7.43

32.19 ± 8.01

Urinary creatinine (mmol/l)

   CD

3.77 ± 0.53

4.08 ± 0.84

4.13 ± 1.00

4.43 ± 0.87

   HSFD

4.05 ± 0.72

4.20 ± 0.92

4.08 ± 0.76

4.71 ± 0.69

   HSFD+Ibrolipim

3.92 ± 0.68

4.17 ± 0.96

4.20 ± 1.01

4.48 ± 0.49

  1. Values are means ± SD, n = 5 in each group; * P < 0.05, ** P < 0.01 vs. CD group; # P < 0.05, ## P < 0.01 vs. HSFD group.