Comparison of effects of diet versus exercise weight loss regimens on LDL and HDL particle size in obese adults

Table 1 LDL and HDL particle size and distribution at baseline and post-treatment

	Group	Week 1 ^a		Week 12		P-value within group ^b	P-value between groups ^c
		Mean	SEM	Mean	SEM
LDL integrated particle size (Å)	ADF	261	± 1	265	± 2	0.01	0.20
	CR	260	± 2	264	± 2	0.01
	Exercise	260	± 2	261	± 1	0.70
	Control	260	± 2	260	± 2	0.49
% Large LDL particles	ADF	40	± 4	48	± 5	0.04	0.43
	CR	47	± 5	52	± 5	0.07
	Exercise	49	± 4	49	± 4	0.49
	Control	42	± 4	41	± 4	0.53
% Medium LDL particles	ADF	35	± 2	34	± 2	0.75	0.49
	CR	36	± 3	34	± 3	0.57
	Exercise	35	± 2	34	± 2	0.48
	Control	39	± 2	39	± 2	0.87
% Small LDL particles	ADF	25	± 3	18	± 3	0.04	0.75
	CR	18	± 3	14	± 4	0.29
	Exercise	17	± 3	17	± 3	0.89
	Control	19	± 4	20	± 4	0.50
% Large HDL particles	ADF	34	± 3	34	± 3	0.93	0.98
	CR	34	± 4	36	± 5	0.67
	Exercise	28	± 3	34	± 3	0.04
	Control	34	± 4	34	± 5	0.98
% Medium HDL particles	ADF	49	± 3	46	± 3	0.39	0.31
	CR	43	± 4	44	± 4	0.85
	Exercise	52	± 3	52	± 3	0.80
	Control	45	± 3	44	± 4	0.64
% Small HDL particles	ADF	18	± 3	20	± 3	0.61	0.53
	CR	22	± 4	20	± 6	0.57
	Exercise	21	± 4	14	± 3	0.03
	Control	21	± 3	22	± 3	0.60

Values reported as mean ± SEM.
Alternate day fasting (ADF), n = 13; Calorie restriction (CR), n = 12; Exercise, n = 12; Control, n = 12.
^a Baseline values were not significantly different between intervention groups: One-way ANOVA.
^b P-value within group: Student's paired t-test comparing week 1 to week 12 values.
^c P-value between groups: One-way ANOVA between groups for week 12 values.

ISSN: 1476-511X