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Figure 4 | Lipids in Health and Disease

Figure 4

From: Chronic administration of palmitoleic acid reduces insulin resistance and hepatic lipid accumulation in KK-Ay Mice with genetic type 2 diabetes

Figure 4

Effect of palmitoleic acid on lipogenic gene expression in liver in KK-Ay mice. Animals were orally administered vehicle (control), 300 mg/kg of palmitic acid, or 300 mg/kg palmitoleic acid on a daily basis. (A) Relative mRNA expression levels of SREBP-1; (B) Relative mRNA expression levels of FAS; (C) Relative mRNA expression levels of SCD-1. Each value is the mean ± SE, n = 10. Means in a row with superscripts without common letter are different, p < 0.05. C16:0, palmitic acid; C16:1, palmitoleic acid; SREBP-1, sterol regulatory element binding protein 1; SCD-1, stearoyl-coenzyme A desaturase 1; FAS, fatty acid synthase.

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