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Figure 1 | Lipids in Health and Disease

Figure 1

From: Effect of α-linolenic acid on endoplasmic reticulum stress-mediated apoptosis of palmitic acid lipotoxicity in primary rat hepatocytes

Figure 1

Effects of PA on primary rat hepatocytes. (A) Apoptotic cell death elicited by increasing concentrations of palmitic acid (PA). (B) Treatment with PA for 16 h produced significant and concentration-dependent effects on MTT reduction and LDH release. Data represent mean ± S.E.M., n = 5,*P < 0.05 vs. control (0 μmol/l palmitic acid), **P < 0.05 vs. palmitic acid-only cells. (C) Treatment of primary rat hepatocytes with 250 μmol/L PA produced a significant increase in activity of caspase-3. For comparison, the effects of tunicamycin(Tn; 5 μg/ml)are also shown. Data represent mean ± S.E.M., n = 5,*P < 0.05 vs. control (0 μmol/l palmitic acid), **P < 0.05 vs. palmitic acid-only cells.

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Lipids in Health and Disease

ISSN: 1476-511X