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Figure 1 | Lipids in Health and Disease

Figure 1

From: Tropically stable novel oral lipid formulation of amphotericin B (iCo-010): biodistribution and toxicity in a mouse model

Figure 1

Plasma creatinine concentrations (Mean ± SEM; mg/dL) in mice 12 hours following the completion of twice-daily × 5 days treatment course of different doses of iCo-010 (n = 5-6) or 12 hours following the completion of once daily × 5 days IV treatment course of Fungizone® 2 mg/kg (n = 6). Ten (out of 16) animals were lost at different times during the dosing of Fungizone® due to acute toxicity associated with this dose.

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