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Table 3 Logistic regression analyses of different IL-6R genotypes on lipid status among young adolescents a

From: Association between interleukin-6 receptor gene variations and atherosclerotic lipid profiles among young adolescents in Taiwan

  Model type rs4845617 G/A rs4845623 A/G rs8192284 A/C rs2229238 C/T
   OR 95%CI OR 95%CI OR 95%CI OR 95%CI
Boys          
   High CHOL additive 0.91 0.55-1.50 1.10 0.58-2.06 0.90 0.53-1.52 0.81 0.48-1.36
  dominant 0.74 0.29-1.86 0.77 0.09-6.39 1.36 0.53-3.50 1.32 0.51-3.38
  recessive 1.01 0.46-2.19 1.18 0.56-2.47 0.70 0.35-1.42 0.58 0.29-1.17
   High TG additive 0.92 0.61-1.40 1.45 0.85-2.46 0.85 0.54-1.34 0.81 0.51-1.27
  dominant 0.95 0.46-1.97 1.56 0.32-7.50 0.39 0.12-1.32 0.38 0.11-1.26
  recessive 0.86 0.45-1.63 1.55 0.83-2.91 1.04 0.56-1.94 0.95 0.52-1.75
   High HDL-C additive 1.02 0.70-1.49 0.98 0.58-1.64 0.78 0.51-1.18 0.84 0.56-1.27
  dominant 1.35 0.72-2.52 0.51 0.06-4.04 0.68 0.28-1.68 0.79 0.34-1.85
  recessive 0.81 0.45-1.45 1.04 0.58-1.89 0.74 0.43-1.28 0.81 0.46-1.40
   High LDL-C additive 0.78 0.49-1.26 0.81 0.42-1.57 0.83 0.50-1.39 0.81 0.49-1.34
  dominant 0.94 0.41-2.15 - - 1.22 0.48-3.09 1.18 0.46-2.97
  recessive 0.60 0.30-1.21 0.90 0.43-1.90 0.65 0.33-1.27 0.62 0.32-1.22
   High CHOL/HDL-C additive 1.24 0.79-1.93 0.74 0.38-1.43 0.70 0.43-1.16 0.78 0.48-1.27
  dominant 1.39 0.67-2.89 - - 0.30 0.07-1.26 0.45 0.13-1.51
  recessive 1.28 0.61-2.66 0.81 0.39-1.67 0.79 0.41-1.51 0.86 0.45-1.64
Girls          
   High CHOL additive 1.23 0.79-1.93 0.96 0.51-1.79 1.13 0.71-1.80 1.20 0.77-1.88
  dominant 1.15 0.55-2.43 1.78 0.36-8.79 1.51 0.70-3.27 1.60 0.76-3.38
  recessive 1.55 0.71-3.36 0.85 0.41-1.78 0.97 0.49-1.92 1.07 0.54-2.12
   High TG additive 1.59 1.06-2.37 0.57 0.30-1.09 1.58 1.05-2.37 1.55 1.04-2.29
  dominant 1.77 0.95-3.28 - - 1.53 0.77-3.02 1.54 0.79-2.99
  recessive 2.00 0.97-4.11 0.59 0.29-1.19 2.21 1.10-4.44 2.14 1.09-4.20
   High HDL-C additive 1.24 0.83-1.86 0.76 0.41-1.41 1.57 1.03-2.39 1.68 1.12-2.52
  dominant 1.24 0.64-2.41 0.73 0.09-5.94 1.67 0.84-3.32 1.90 0.98-3.67
  recessive 1.46 0.74-2.92 0.74 0.37-1.46 1.98 0.99-4.00 2.16 1.07-4.35
   High LDL-C additive 1.08 0.70-1.65 1.01 0.56-1.82 1.10 0.71-1.71 1.22 0.80-1.86
  dominant 0.87 0.41-1.84 0.75 0.09-6.08 0.77 0.33-1.82 0.99 0.45-2.16
  recessive 1.38 0.68-2.83 1.05 0.53-2.05 1.48 0.74-2.96 1.63 0.81-3.25
   High CHOL/HDL-C additive 1.27 0.83-1.94 0.70 0.37-1.36 1.68 1.08-2.61 1.82 1.18-2.79
  dominant 1.38 0.69-2.75 1.75 0.36-8.56 1.35 0.64-2.86 1.61 0.79-3.27
  recessive 1.38 0.68-2.82 0.57 0.27-1.22 3.17 1.37-7.30 3.47 1.51-8.00
  1. Abbreviation: CHOL, Cholesterol; TG, Triglycerides; HDL-C, High density lipoprotein-cholesterol; LDL-C, Low density lipoprotein-cholesterol.
  2. additive model: major-homozygotes v.s. heterozygotes v.s. minor-homozygotes, reference group: major-homozygotes.
  3. dominant model: major-homozygotes/heterozygotes v.s. minor-homozygotes, reference group: major-homozygotes/heterozygotes.
  4. recessive model: major-homozygotes v.s. heterozygotes/minor-homozygotes; reference group: major-homozygotes.
  5. a All abnormal variables defined as age- and gender-specific 90th percentile cut-off point of study variables and OR was adjusted for age, cigarette smoking, alcohol drinking, and puberty status.