Plasma HDL cholesterol and ApoA-I levels according to the different combinations of tHcy and tCys levels. A. plasma HDL cholesterol levels. B. plasma ApoA-I levels. Analyses of covariance (ANCOVA) were performed using the general linear model within different combinations of tHcy and tCys. Bars are mean ± SEM, white bars are unadjusted, black bars are adjusted for age, gender, smoke, hypertension, fasting plasma glucose, and creatinine. Both P < 0.001 for trend, ns indicates no significant.