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Table 4 Unadjusted and adjusted risk for CAD prevalence with increasing quartiles of tHcy and tCys levels

From: Relationship between lipid profiles and plasma total homocysteine, cysteine and the risk of coronary artery disease in coronary angiographic subjects

 

Q1

Q2

Q3

Q4

P for trend

tHcy (μmol/L)

<9.1

9.1-12.3

12.4-16.5

>16.5

 

CAD

228(44.5%)

255(49.9%)

280(53.8%)

290(56.3%)

 

Unadjusted OR (95% CI)

1.0(referent)

1.24(0.97-1.58)

1.45(1.14-1.85)

1.61(1.26-2.05)

P < 0.001

Adjusted OR* (95% CI)

1.0(referent)

1.08(0.83-1.39)

1.12(0.87-1.44)

1.35(1.04-1.74)

P < 0.001

Adjusted OR† (95% CI)

1.0(referent)

1.04(0.80-1.36)

1.14(0.88-1.47)

1.34(1.03-1.74)

P < 0.001

tCys (μmol/L)

<219.5

219.5-250.2

250.3-284.1

>284.1

 

CAD

259(50.6%)

261(50.5%)

260(50.4%)

273(53.2%)

 

Unadjusted OR (95% CI)

1.0(referent)

0.99(0.78-1.27)

0.98(0.77-1.26)

1.11(0.87-1.42)

NS

Adjusted OR* (95% CI)

1.0(referent)

1.04(0.81-1.34)

1.05(0.82-1.35)

1.16(0.90-1.49)

NS

Adjusted OR† (95% CI)

1.0(referent)

1.02(0.79-1.32)

1.07(0.83-1.38)

1.17(0.91-1.52)

NS

  1. * Adjusted for age and gender.
  2. † Adjusted for age, gender, smoke, hypertension, triglycerides, HDL, ApoA-I, fasting plasma glucose, creatinine.
  3. CI = confidence interval, OR = odds ratio, Q1 = quartile 1, Q2 = quartile 2, Q3 = quartile 3, Q4 = quartile 4.