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Table 4 Unadjusted and adjusted risk for CAD prevalence with increasing quartiles of tHcy and tCys levels

From: Relationship between lipid profiles and plasma total homocysteine, cysteine and the risk of coronary artery disease in coronary angiographic subjects

  Q1 Q2 Q3 Q4 P for trend
tHcy (μmol/L) <9.1 9.1-12.3 12.4-16.5 >16.5  
CAD 228(44.5%) 255(49.9%) 280(53.8%) 290(56.3%)  
Unadjusted OR (95% CI) 1.0(referent) 1.24(0.97-1.58) 1.45(1.14-1.85) 1.61(1.26-2.05) P < 0.001
Adjusted OR* (95% CI) 1.0(referent) 1.08(0.83-1.39) 1.12(0.87-1.44) 1.35(1.04-1.74) P < 0.001
Adjusted OR (95% CI) 1.0(referent) 1.04(0.80-1.36) 1.14(0.88-1.47) 1.34(1.03-1.74) P < 0.001
tCys (μmol/L) <219.5 219.5-250.2 250.3-284.1 >284.1  
CAD 259(50.6%) 261(50.5%) 260(50.4%) 273(53.2%)  
Unadjusted OR (95% CI) 1.0(referent) 0.99(0.78-1.27) 0.98(0.77-1.26) 1.11(0.87-1.42) NS
Adjusted OR* (95% CI) 1.0(referent) 1.04(0.81-1.34) 1.05(0.82-1.35) 1.16(0.90-1.49) NS
Adjusted OR (95% CI) 1.0(referent) 1.02(0.79-1.32) 1.07(0.83-1.38) 1.17(0.91-1.52) NS
  1. * Adjusted for age and gender.
  2. † Adjusted for age, gender, smoke, hypertension, triglycerides, HDL, ApoA-I, fasting plasma glucose, creatinine.
  3. CI = confidence interval, OR = odds ratio, Q1 = quartile 1, Q2 = quartile 2, Q3 = quartile 3, Q4 = quartile 4.