Figure 3

The linkage disequilibria (LD) among the five SNPs. (A) ApoA1 -75bp G>A, (B) ApoC3 3238C>G, (C) ApoA5 -1131T>C, (D) ApoA5 c.457G>A, and (E) ApoA5 c.553G>T. ApoA1 -75bp G>A was in LD with ApoC3 3238C>G (LD correlation coefficient r = 0.410, P < 0.001), ApoA5 -1131T>C (r = 0.064, P < 0.04), ApoA5 c.553G>T (r = 0.106, P < 0.001), and ApoA5 c.457G>A (r = 0.096, P < 0.002). ApoC3 3238C>G was in LD with ApoA5 -1131T>C (r = 0.359, P < 0.001). ApoA5 -1131T>C was in LD with ApoA5 c.553G>T (r = 0.245, P < 0.001) and ApoA5 c.457G>A (r = 0.165, P < 0.001). There was no LD between ApoC3 3238C>G and ApoA5 c.553G>T (r = 0.059, P = 0.059) or ApoA5 c.457G>A (r = 0.044, P = 0.155); and between ApoA5 c.553G>T and ApoA5 c.457G>A (r = 0.048, P = 0.126).