Table 2 The genotypic and allelic frequencies of ApoA1/C3/A5 gene polymorphisms between males and females
From: Apolipoprotein A1/C3/A5 haplotypes and serum lipid levels
SNP | Group | n | Genotype [n (%)] | Allele [n (%)] | |||
|---|---|---|---|---|---|---|---|
| Â | Â | Â | AA | AB | BB | A | B |
ApoA1 -75bp G>A | Male | 492 | 192(39.0) | 242(49.2) | 58(11.8) | 626(63.6) | 358(36.4) |
(rs1799837) | Female | 538 | 210(39.0) | 264(49.1) | 64(11.9) | 684(63.6) | 392(36.4) |
|  | χ2 | - | 0.003 | 0.001 | |||
| Â | P | - | 0.998 | 0.982 | |||
ApoC3 3238C>G | Male | 492 | 252(51.2) | 192(39.0) | 48(9.8) | 696(70.7) | 288(29.3) |
(rs5128) | Female | 538 | 216(40.2) | 264(49.0) | 58(10.8) | 696(64.7) | 380(35.3) |
|  | χ2 | - | 13.053 | 8.579 | |||
| Â | P | - | 0.002 | 0.003 | |||
ApoA5 -1131T>C | Male | 492 | 268(54.4) | 178(36.2) | 46(9.4) | 714(72.6) | 270(27.4) |
(rs662799) | Female | 538 | 266(49.4) | 226(42.0) | 46(8.6) | 758(70.4) | 318(29.6) |
|  | χ2 | - | 3.663 | 1.127 | |||
| Â | P | - | 0.160 | 0.288 | |||
ApoA5 c.553G>T | Male | 492 | 466(94.7) | 26(5.3) | 0 | 958(97.4) | 26(2.6) |
(rs2075291) | Female | 538 | 496(92.2) | 42(7.8) | 0 | 1034(96.1) | 42(3.9) |
|  | χ2 | - | 2.651 | 2.561 | |||
| Â | P | - | 0.103 | 0.109 | |||
ApoA5 c.457G>A | Male | 492 | 424(86.2) | 64(13.0) | 4(0.8) | 912(92.7) | 72(7.3) |
(rs3135507) | Female | 538 | 484(90.0) | 48(8.9) | 6(1.1) | 1016(94.4) | 60(5.6) |
|  | χ2 | - | 4.605 | 2.597 | |||
| Â | P | - | 0.100 | 0.107 | |||