From: Apolipoprotein A1/C3/A5 haplotypes and serum lipid levels
Lipid parameter | Risk factor | χ2 | P | Odds ratio | 95% CI |
---|---|---|---|---|---|
Male plus female | Â | Â | Â | Â | Â |
   TC | ApoA5 -1131T>C allele | 12.284 | 0.000 | 1.704 | 1.265-2.295 |
   TG | ApoA5 c.553G>T genotype | 5.986 | 0.014 | 2.293 | 1.180-4.460 |
 | ApoA5 c.457 G>A allele | 7.713 | 0.005 | 2.243 | 1.268-3.968 |
 | ApoA5 -1131T>C allele | 6.647 | 0.010 | 1.534 | 1.108-2.123 |
 | ApoA1 -75bp G>A genotype | 5.337 | 0.021 | 0.345 | 0.140-0.851 |
   HDL-C | ApoA5 c.457 G>A allele | 7.595 | 0.006 | 16.571 | 2.250-12.048 |
   LDL-C | ApoC3 3238C>G genotype | 12.001 | 0.001 | 2.834 | 1.572-5.111 |
   ApoA1 | ApoA5 c.553G>T genotype | 4.978 | 0.026 | 11.297 | 1.343-5.052 |
   ApoB | ApoC3 3238C>G genotype | 13.034 | 0.000 | 1.514 | 1.209-1.897 |
Male | Â | Â | Â | Â | Â |
   TC | ApoA5 -1131T>C genotype | 4.910 | 0.027 | 1.428 | 1.042-1.957 |
   TG | ApoA5 c.553G>T genotype | 17.322 | 0.000 | 7.990 | 3.003-21.260 |
 | ApoA5 c.457 G>A allele | 4.097 | 0.043 | 2.263 | 1.026-4.989 |
 | ApoA5 -1131T>C allele | 7.400 | 0.007 | 2.590 | 1.305-5.143 |
 | ApoC3 3238C>G allele | 3.904 | 0.048 | 0.503 | 0.254-0.995 |
 | ApoA1 -75bp G>A genotype | 5.372 | 0.020 | 0.240 | 0.072-0.802 |
   LDL-C | ApoC3 3238C>G genotype | 8.307 | 0.004 | 1.886 | 1.225-2.904 |
   ApoB | ApoA5 c.457 G>A genotype | 4.600 | 0.032 | 0.464 | 0.230-0.936 |
 | ApoC3 3238C>G genotype | 4.284 | 0.038 | 2.088 | 1.040-4.193 |
   ApoA1/ApoB | ApoC3 3238C>G allele | 6.836 | 0.009 | 0.354 | 0.163-0.771 |
 | ApoA1 -75bp G>A allele | 3.939 | 0.047 | 6.065 | 1.023-35.968 |
Female | Â | Â | Â | Â | Â |
   TC | ApoA5 -1131T>C allele | 19.701 | 0.000 | 2.651 | 1.724-4.078 |
   TG | ApoC3 3238C>G genotype | 26.171 | 0.000 | 3.149 | 2.029-4.887 |
   ApoB | ApoA5 c.457 G>A allele | 7.720 | 0.005 | 2.961 | 1.377-6.368 |
 | ApoA5 -1131T>C genotype | 5.390 | 0.020 | 1.600 | 1.076-2.379 |
 | ApoC3 3238C>G allele | 14.382 | 0.000 | 3.403 | 1.807-6.407 |
 | ApoA1 -75bp G>A genotype | 6.842 | 0.009 | 3.043 | 1.322-7.007 |
 | ApoA1 -75bp G>A allele | 4.409 | 0.036 | 0.318 | 0.109-0.927 |
   ApoA1/ApoB | ApoA5 -1131T>C genotype | 7.771 | 0.005 | 6.339 | 1.730-23.221 |
 | ApoC3 3238C>G allele | 5.542 | 0.019 | 13.522 | 1.546-118.228 |
 | ApoA1 -75bp G>A genotype | 5.519 | 0.019 | 14.950 | 1.566-142.771 |
 | ApoA1 -75bp G>A allele | 7.989 | 0.005 | 0.017 | 0.001-0.287 |