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Table 4 Effect of supplementation of a hydrogenated trans fat and a corn-oil based low trans structured fat on plasma, hepatic and fecal lipid levels in apo E-/- mice.

From: Differential effect of corn oil-based low trans structured fat on the plasma and hepatic lipid profile in an atherogenic mouse model: comparison to hydrogenated trans fat

 

CS

LC

Plasma lipids

  

   Free fatty acid (mmol/L)

1.14 ± 0.03

1.11 ± 0.04

   Triglyceride (mmol/L)

1.46 ± 0.09

2.09 ± 0.08***

   Total-C (mmol/L)

16.45 ± 0.81

18.75 ± 0.37*

   HDL-C (mmol/L)

0.11 ± 0.02

0.81 ± 0.06***

   HDL-C/Total-C (%)

0.60 ± 0.06

4.06 ± 0.39***

   Atherogenic indexa

174.95 ± 18.05

23.39 ± 1.99***

   Apo A-I (mg/dL)

4.46 ± 0.57

7.47 ± 0.25***

   Apo B (mg/dL)

21.00 ±0.54

17.19 ± 0.60***

Hepatic lipids

  

   Cholesterol (mmol/g liver)

7.88 ± 0.03

5.83 ± 0.19***

   Triglyceride (mmol/g liver)

7.21 ± 0.34

5.27 ± 0.18**

Fecal lipids

  

   Cholesterol (μmol/g)

4.60 ± 0.28

6.44 ± 0.37**

   Triglyceride (μmol/g)

2.22 ± 0.54

4.44 ± 0.85*

  1. Data are mean ± S.E. (n = 10). Values are significantly different from the CS group according to Student's t test: *P < .05, **P < .01, ***P < .001. C:cholesterol.
  2. a Atherogenic index: (Total-C-HDL-C)/HDL-C
  3. CS, commercial shortening; LC, low trans structured fat from corn oil