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Table 5 Effect of supplementation of a hydrogenated trans fat and a corn-oil based low trans structured fat on the enzyme activities related to the hepatic fatty acid metabolism in apo E-/- mice.

From: Differential effect of corn oil-based low trans structured fat on the plasma and hepatic lipid profile in an atherogenic mouse model: comparison to hydrogenated trans fat

 

CS

LC

Fatty acid synthesis

   G6PD (nmol/min/mg protein)

24.90 ± 2.74

7.42 ± 0.30***

   ME (nmol/min/mg protein)

217.4 ± 18.64

126.58 ± 15.32**

Fatty acid oxidation

   β-oxidation (μmol/min/mg protein)

0.43 ± 0.08

5.42 ± 1.13*

   CPT (nmol/min/mg protein)

19.86 ± 1.42

27.09 ± 1.56**

  1. Data are mean ± S.E. (n = 10). Values are significantly different from the CS group according to Student's t test: *P < .05, **P < .01, ***P < .001. G6PD, glucose-6-phosphate dehydrogenase; ME, malic enzyme; CPT, carnitine palmitoyl transferase.
  2. CS, commercial shortening; LC, low trans structured fat from corn oil