Soybean glycinin improves HDL-C and suppresses the effects of rosuvastatin on hypercholesterolemic rats

Table 1 Compositions of experimental diets

Ingredients	STD	HC	HC+11S	HC+ROS	HC+11S+ ROS
Casein¹	14.74	14.74	14.74	14.74	14.74
Starch	45.83	44.33	44.33	44.33	44.33
Starch dextrinated	15.5	15.5	15.5	15.5	15.5
Sucrose	10	10	10	10	10
Soybean oil	4	4	4	4	4
Cellulose	5	5	5	5	5
Mineral mix²	3.5	3.5	3.5	3.5	3.5
Vitamin mixture²	1	1	1	1	1
L-Cystine	0.18	0.18	0.18	0.18	0.18
Choline bitartrate	0.25	0.25	0.25	0.25	0.25
Cholesterol³	0	1	1	1	1
Cholic acid¹	0	0.5	0.5	0.5	0.5
Treatment
Glycinin (mg/kg/dia)	-	-	300	-	300
Rosuvastatin (mg/kg/dia)	-	-	-	10	10

STD = standard diet, AIN-93 Composition; HC = hypercholesterolemic diet: AIN-93 plus 1 g/100 g cholesterol and 0.5 g/100 g cholic acid; HC+11S = HC diet + glycinin (300 mg/kg/day); HC+ROS = HC diet + rosuvastatin (10 mg/kg/day); HC+11S+ROS = HC diet + glycinin (300 mg/kg/day) and rosuvastatin (10 mg/kg/day). ¹Sigma-Aldrich, Co., USA. ²PragSoluções^®, Co., Brazil. ³Reagen, Co., USA.

ISSN: 1476-511X