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Table 3 Effect of diets on plasma lipid profile and hepatic lipid content in rats

From: Soybean glycinin improves HDL-C and suppresses the effects of rosuvastatin on hypercholesterolemic rats

  STD HC HC+11S HC+ROS HC+11S+ ROS
Plasma      
   TC (mmol/L) 1.56 ± 0.07b 4.24 ± 0.45ª 3.77 ± 0.41ª 3.14 ± 0.12ª 4.33 ± 0.40ª
   HDL-C (mmol/L) 0.78 ± 0.03b 0.82 ± 0.06b 1.04 ± 0.04ª 0.73 ± 0.04b 0.73 ± 0.08b
   non-HDL-C (mmol/L) 0.78 ± 0.04b 3.42 ± 0.47ª 2.74 ± 0.4ª 2.43 ± 0.16ª 3.57 ± 0.42ª
   TG (mmol/L) 0.48 ± 0.02b 1.09 ± 0.12ª 0.85 ± 0.11ª 0.84 ± 0.07ª 0.81 ± 0.08ª
Liver      
   TC (μmol/g) 7.15 ± 0.34d 57.66 ± 1.06b 54.97 ± 2.12b 36.15 ± 2.12c 76.66 ± 2.12ª
   TG (μmol/g) 14.52 ± 0.91c 58.77 ± 3.97ª 46.48 ± 4.06b 41.35 ± 2.43b 46.74 ± 3.08b
Atherogenic index 1.01 ± 0.05c 4.62 ± 0.87ab 2.67 ± 0.38bc 3.49 ± 0.42ab 5.06 ± 0.81a
  1. STD = standard diet, AIN-93 Composition; HC = hypercholesterolemic diet: AIN-93 plus 1 g/100 g cholesterol and 0.5 g/100 g cholic acid; HC+11S = HC diet + glycinin (300 mg/kg/day); HC+ROS = HC diet + rosuvastatin (10 mg/kg/day); HC+11S+ROS = HC diet + glycinin (300 mg/kg/day) and rosuvastatin (10 mg/kg/day). Values are represented as mean ± SEM. TC = total cholesterol; HDL-C = high density lipoprotein; non-HDL-C = difference between TC and HDL-C; TG = triglycerides; atherogenic index = non-HDL-C/HDL-C. Different superscript letters in the same row indicate a significant difference (p < 0.05) between experimental groups.