Table 2 Features of 1,764 PC patients grouped according to VAD classes.
| Â | PC patients with VAD absent No 1362 | PC patients with Mild VAD No 126 | PC patients with Moderate VAD No 141 | PC patients with Severe VAD No 135 | Â |
|---|---|---|---|---|---|
|  |  |  |  |  | p § |
Females/Males | 903/459 | 84/42 | 102/39 | 90/45 | 0.427 |
|  | Mean ± SD | Mean ± SD | Mean ± SD | Mean ± SD |  |
Age (years) | 44.46 ± 17.80 | 58.81 ± 14.56 | 59.22 ± 15.32 | 59.28 ± 15.38 | < 0.001 |
BMI (Kg/m 2 ) | 23.71 ± 3.62 | 26.14 ± 4.68 | 25.92 ± 4.86 | 26.53 ± 4.61 | < 0.001 |
WC (cm) | 82.73 ± 10.76 | 90.94 ± 12.51 | 90.65 ± 13.89 | 92.52 ± 13.09 | < 0.001 |
| Â | No (%) | No (%) | No (%) | No (%) | Â |
Metabolic Syndrome* | 62 (4.6) | 40 (31.7) | 52 (36.9) | 88 (65.2) | < 0.001 |
Diabetes or fasting glucose ≥ 5.6 mmol/l | 184 (13.5) | 43 (34.1) | 41 (29.1) | 52 (38.5) | < 0.001 |
Only diabetes | 64 (4.7) | 22 (17.5) | 22 (15.6) | 29 (21.5) | < 0.001 |
High Blood pressure | 262 (19.2) | 55 (43.7) | 62 (44) | 73 (54.1) | < 0.001 |
High Triglycerides | 31 (2.3) | 41 (32.5) | 80 (56.7) | 123 (91.1) | < 0.001 |
Low HDL Cholesterol | 215 (15.8) | 50 (39.7) | 81 (57.4) | 92 (68.1) | < 0.001 |
Increased WC | 165 (12.1) | 38 (30.29) | 49 (34.8) | 54 (40.0) | < 0.001 |
Classes of obesity** | Â | Â | Â | Â | Â |
Underweight | 16 (1.2) | 1 (0.8) | 1 (0.7) | - | 0.178 |
Normal weight | 1052 (77.2) | 68 (54) | 75 (53.2) | 67 (49.6) | < 0.001 |
Overweight | 209 (15.3) | 39 (31) | 42 (29.8) | 45 (33.3) | < 0.001 |
Obese class I | 65 (4.8) | 10 (7.9) | 16 (11.3) | 18 (13.3) | < 0.001 |
Obese class II | 19 (1.4) | 7 (5.6) | 6 (4.3) | 2 (1.5) | 0.082 |
Obese class III | 1 (0.1) | 1 (0.8) | 1 (0.7) | 3 (2.2) | < 0.001 |
CHD or MI | 13 (1) | 7 (5.6) | 10 (7.1) | 14 (10.4) | < 0.001 |
TIA or IS | 21 (1.5) | 9 (7.1) | 14 (9.9) | 15 (11.1) | < 0.001 |
|  | Mean ± SD | Mean ± SD | Mean ± SD | Mean ± SD |  |
Fasting glucose (mmol/l) | 5.11 ± 1.26 | 5.71 ± 1.66 | 5.59 ± 1.77 | 5.80 ± 2.37 | < 0.001 |
AST (UI/l) | 21.46 ± 19.45 | 24.03 ± 17.85 | 20.11 ± 6.39 | 25.48 ± 22.39 | 0.104 |
ALT (UI/l) | 20.99 ± 11.69 | 24.45 ± 17.33 | 20.32 ± 7.80 | 25.52 ± 19.24 | 0.002 |
GFR (ml/min/1.73 m 2 )*** | 73.11 ± 25.78 | 65.14 ± 25.79 | 60.19 ± 33.65 | 64.53 ± 32.29 | < 0.001 |
Total Cholesterol (mmol/l) | 4.88 ± 0.75 | 5.12 ± 0.94 | 5.35 ± 0.99 | 5.51 ± 0.95 | < 0.001 |
HDL cholesterol (mmol/l) | 1.41 ± 0.24 | 1.25 ± 0.22 | 1.18 ± 0.22 | 1.10 ± 0.23 | < 0.001 |
Triglycerides (mmol/l) | 0.99 ± 0.31 | 1.56 ± 0.32 | 1.78 ± 0.38 | 2.72 ± 0.97 | < 0.001 |
LDL Cholesterol (mmol/l)**** | 3.01 ± 0.69 | 3.15 ± 0.86 | 3.35 ± 0.91 | 3.16 ± 0.97 | < 0.001 |
HbA1c (%) Only in subgroup of diabetic patients | 6.45 ± 1.40 | 7.04 ± 1.45 | 6.79 ± 1.18 | 7.48 ± 1.50 | 0.361 |