Positive association of the hepatic lipase gene polymorphism c.514C > T with estrogen replacement therapy response

Table 5 Results of the paired-samples t-tests (before and after treatment) according to genotype

Genotype	Variable (mg/dL)	N	Mean	Standard Deviation	t-test	p
CC	TotalChol	15	216.27	47.36	0.15	0.89
	TotalChol 2	15	214.60	39.09
CT	TotalChol	29	205.41	44.03	0.08	0.94
	TotalChol 2	29	204.66	39.76
TT	TotalChol	14	214.07	48.65	0.03	0.98
	TotalChol 2	14	213.71	55.03
CC	HDL-C	15	57.87	12.56	1.31	0.21
	HDL-C 2	15	54.87	15.47
CT	HDL-C	29	57.17	12.18	0.21	0.84
	HDL-C 2	29	56.76	13.38
TT	HDL-C	14	63.79	16.44	0.36	0.72
	HDL-C 2	14	62.93	15.16
CC	LDL-C	15	134.40	42.83	-0.09	0.93
	LDL-C2	15	135.40	34.27
CT	LDL-C	29	118.21	31.19	-0.14	0.89
	LDL-C2	29	19.62	38.01
TT	LDL-C	14	108.50	45.96	-1.26	0.23
	LDL-C2	14	127.14	42.28
CC	TG	15	132.60	45.50	1.07	0.30
	TG2	15	121.13	44.02
CT	TG	29	136.41	70.19	1.20	0.24
	TG2	29	121.83	73.78
TT	TG	14	147.36	76.01	1.71	0.11
	TG2	14	123.57	74.68

TotalChol: total pre-treatment cholesterol; HDL-C: pre-treatment high-density lipoprotein cholesterol; LDL-C: pre-treatment low-density lipoprotein cholesterol; TG: pre-treatment triglycerides; TotalChol2: total post-treatment cholesterol; HDL-C2: post-treatment high-density lipoprotein cholesterol; LDL-C2: post-treatment low-density lipoprotein cholesterol; TG2: post-treatment triglycerides; CC: homozygous major-allele genotype; CT: heterozygous genotype; TT: homozygous minor-allele genotype.

ISSN: 1476-511X