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Figure 4 | Lipids in Health and Disease

Figure 4

From: Effects of undenatured whey protein supplementation on CXCL12- and CCL21-mediated B and T cell chemotaxis in diabetic mice

Figure 4

Whey protein restores B cell chemotaxis in diabetic mice. Splenic B cells were isolated from 10 mice in each group and were analyzed for migration to CXCL12 and CCL21. Input populations and migrated cell populations were stained with B220-APC and IgD-PE/CD44-FITC. Representative dot plots of input cells and transmigrated cells to medium (without chemokine) versus medium containing CXCL12 for control mice are shown, including the input and transmigrated B cell population data. Data from one representative experiment are shown in panel A. The percentage of B cells from 10 different mice in the control (open bars), diabetic (closed, black bars) and WP-treated diabetic (closed, gray bars) groups that specifically migrated to chemokines are shown. The results are expressed as the mean specific migration ± SEM. * P < 0.05, diabetic vs. control; #P < 0.05, diabetic vs. WP-treated groups.

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Lipids in Health and Disease

ISSN: 1476-511X