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Table 1 Parameters of mice from Control and HFD groups receiving chow and high fat diet, respectively or Colitis and Colitis + HFD groups, receiving the respective diets and treated with 2 cycles of DSS (3%) to induce ulcerative colitis

From: The combination of high-fat diet-induced obesity and chronic ulcerative colitis reciprocally exacerbates adipose tissue and colon inflammation

Parameter

Control

Colitis

HFD

Colitis+HFD

Food intake (kcal/mouse)

67.07 ± 3.65a

62.47 ± 2.48a

112.8 ± 3.92b

104.9 ± 4.20b

Liquid Intake (mL/mouse)

59.00 ± 3.98a

53.28 ± 2.90a

39.91 ± 2.35b

29.99 ± 0.95b

Total weight gain (g)

8.36 ± 0.82a

5.84 ± 0.66a

10.58 ± 0.81b

7.53 ± 0.85a

OGTT (A.U.C)1

656.9 ± 28.5a

668.9 ± 28.5a

844.4 ± 27.8b

918.2 ± 53.6b

AKT mRNA2 (adipose tissue)

0.67 ± 0.23

0.33 ± 0.12

0.30 ± 0.02

0.58 ± 0.14

GLUT4 mRNA2 (adipose tissue)

0.96 ± 0.35

0.50 ± 0.14

0.82 ± 0.33

0.98 ± 0.23

  1. 1OGTT: oral glucose tolerance test. AUC (area under the curve), 2 mRNA expressed as fold increase compared to control. Results expressed as mean ± standard error. ANOVA + Newman-Keuls post-test, Different letters in a same row = p < 0.05. n = 5 to 7/group.