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Table 2 Demographics and baseline characteristics of patients with increases/no change or decreases from baseline in HDL-C at endpoint

From: Low incidence of paradoxical reductions in HDL-C levels in dyslipidemic patients treated with fenofibrate alone or in combination with ezetimibe or ezetimibe/simvastatin

 

HDL-C increase and

no change

HDL-C decrease

All patients

Demographic Parameters

Mean age ± SD, years (n)

54.6 ± 10.3 (715)

52.6 ± 10.8 (139)

54.3 ± 10.4 (854)

   <65 years, n (%)

578 (80.8%)

122 (87.8%)

700 (82.0%)

   ≥65 years, n (%)

137 (19.2%)

17 (12.2%)

154 (18.0%)

Gender, n (%)

   

   Female

340 (47.6%)

57 (47.6%)

397 (46.5%)

   Male

375 (52.4%)

82 (59.0%)

457 (53.5%)

Race category, n (%)

   

   Caucasian

561 (78.5%)

111 (79.9%)

672 (78.7%)

   Non-Caucasian

154 (21.5%)

28 (20.1%)

182 (21.3%)

History of diabetes, n (%)

86 (12.0%)

20 (14.4%)

106 (12.4%)

Baseline Parameters, mmol/L (n)

Mean HDL ± SD

1.1 ± 0.2 (715)

1.2 ± 0.3 (139)

1.1 ± 0.2 (854)

Mean Apo AI ± SD (g/L)

1.5 ± 0.2 (706)

1.6 ± 0.4 (134)

1.5 ± 0.3 (840)

Mean LDL-C ± SD

4.2 ± 0.7 (715)

4.2 ± 0.7 (139)

4.2 ± 0.7 (854)

Mean Apo B ± SD (g/L)

1.7 ± 0.2 (706)

1.6 ± 0.3 (134)

1.6 ± 0.2 (840)

Mean Non-HDL-C ± SD

5.6 ± 0.8 (715)

5.4 ± 0.8 (139)

5.6 ± 0.8 (854)

Mean TC ± SD

6.7 ± 0.9 (715)

6.6 ± 0.8 (139)

6.7 ± 0.8 (854)

Median TG ± SD

2.9 ± 1.0 (715)

2.7 ± 1.1 (139)

2.9 ± 1.0 (854)

  1. Apo = apolipoprotein; LDL-C = low-density lipoprotein cholesterol; HDL-C = high-density lipoprotein cholesterol; SD = standard deviation; TC = total cholesterol; TG = triglycerides