| Control subjects, n = 1086 | Case patients, n = 557 |  | ||
---|---|---|---|---|---|
 | N | % | N | % | P |
Gender | Â | Â | Â | Â | 0.77 |
   Men | 800 | 73.7 | 414 | 74.3 |  |
   Women | 286 | 26.3 | 143 | 25.7 |  |
Hypertension | 129 | 11.9 | 402 | 72.3 | <.0001 |
Diabetes mellitus | 51 | 4.7 | 213 | 38.3 | <.0001 |
Smoking | 102 | 9.4 | 163 | 29.3 | <.0001 |
Alcohol drinking | 600 | 55.3 | 144 | 25.9 | <.0001 |
Old stroke | 7 | 0.6 | 58 | 10.4 | <.0001 |
Hypolipidemic medication | 121 | 11.1 | 185 | 33.2 | <.0001 |
Glomerular filtration rate, ml/min/1.73 m2 | Â | Â | <.0001 | ||
< = 60 | 215 | 19.8 | 188 | 37.1 | Â |
60.1-90 | 787 | 72.5 | 246 | 48.5 | Â |
> 90 | 84 | 7.7 | 73 | 14.4 | Â |
 | Mean | SD | Mean | SD |  |
Age, yr | 64.3 | 10.6 | 67.5 | 9.6 | <.0001 |
BMI, kg/m2 | 24.4 | 3.0 | 24.7 | 3.7 | 0.07 |
Systolic BP, mmHg | 124.8 | 14.1 | 135.7 | 26.0 | <.0001 |
Diastolic BP, mmHg | 72.4 | 9.2 | 73.1 | 16.0 | 0.36 |
Total cholesterol, mg/dL | 177.7 | 27.6 | 162.6 | 31.8 | <.0001 |
Triglycerides, mg/dL | 126.3 | 84.6 | 133.1 | 99.9 | 0.17 |
HDL cholesterol, mg/dL | 44.5 | 11.2 | 34.7 | 11.9 | <.0001 |
LDL cholesterol, mg/dL | 97.5 | 22.1 | 95.5 | 23.0 | 0.10 |
Serum creatinine, mg/dL | 1.12 | 0.45 | 1.52 | 1.47 | <.0001 |
Estimated glomerular filtration rate, ml/min/1.73 m2 | 70.0 | 15.0 | 64.6 | 25.6 | <.0001 |