Group | α-lipoic acid + exercise (n = 12) | α-lipoic acid only (n = 12) | ||||
---|---|---|---|---|---|---|
Time | Baseline | Pre intervention | Post intervention | Baseline | Pre intervention | Post intervention |
Body mass (kg) | 87.7 (18.7) | 87.3 (18.9) | 85.5 (17.4) | 93.1 (14.3) | 93.1 (14.3) | 92.4 (14.0) |
BMI (kg/m2) | 31.6 (6.7) | 31.4 (6.9) | 30.7 (6.4) | 32.8 (5.8) | 32.8 (5.8) | 32.5 (5.7) |
Total body fat (%) | 46.6 (6.9) | 41.6 (5.5) | 41.5 (5.4)† | 49.8 (11.6) | 49.4 (11.2) | 49.3 (11.8) |
Waist circumference (cms) | 105.8 (23.3) | 100.6 (13.9) | 96.1 (13.9)† | 104.9 (9.0) | 104.9 (9.0) | 102.7 (9.2) |
Hip circumference (cms) | 109.9 (13.9) | 108.8 (16.0) | 103.1 (13.1)† | 112.5 (12.7) | 112.6 (12.8) | 111.1 (12.9) |
Total cholesterol (mmol.L-1) | 5.5 (1.0) | 5.5 (0.6) | 5.2 (1.0) | 4.7 (1.2) | 4.7 (1.2) | 4.8 (1.1) |
HDL cholesterol (mmol.L-1) | 1.2 (0.2) | 1.3 (0.2) | 1.1 (0.1) | 1.1 (0.3) | 1.1 (0.3) | 1.1 (0.2) |
LDL cholesterol (mmol.L-1) | 3.3 (0.9) | 3.4 (0.7) | 3.2 (0.9) | 3.0 (1.1) | 3.0 (1.1) | 3.1 (1.1) |
Triglycerides (mmol.L-1) | 1.9 (1.1) | 1.7 (0.7) | 1.8 (0.8) | 1.6 (0.7) | 1.6 (0.7) | 1.7 (0.7) |
hs- CRP (mg/l) | 6.2 (5.4) | 6.0 (5.7) | 6.3 (7.5) | 4.6 (5.0) | 4.6 (5.0) | 4.6 (5.1) |
Homocysteine (μmol/l) | 11.7 (6.8) | 11.2 (3.6) | 11.7 (5.1) | 12.1 (4.5) | 12.1 (4.6) | 12.2 (4.6) |
Glucose (mmol.L-1) | 5.9 (0.9) | 5.7 (0.6) | 5.6 (0.7) | 6.1 (1.0) | 6.1 (1.0) | 6.0 (0.8) |
% HbA1c | 5.9 (0.3) | 5.9 (0.3) | 5.7 (0.4) | 6.0 (0.5) | 6.0 (0.5) | 6.2 (1.1) |
Systolic BP (mmHg) | 143.0 (26.2) | 139.2 (20.6) | 141.5 (16.9) | 141.4 (12.7) | 143.2 (12.8) | 136.2 (15.4) |
Diastolic BP (mmHg) | 90.5 (11.6) | 88.3 (11.2) | 90.3 (11.9) | 88.9 (8.6) | 90.7 (10) | 89.6 (12.7) |