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Figure 1 | Lipids in Health and Disease

Figure 1

From: Oral bioavailability of the ether lipid plasmalogen precursor, PPI-1011, in the rabbit: a new therapeutic strategy for Alzheimer's disease

Figure 1

Time course (1 to 48 hr) of conversion of PPI-1011 to free DHA and DHA-containing plasmalogens (Pls) and phosphatidylethanolamines (Ptd). Plasma levels are normalized to levels of the housekeeping metabolite PtdEtn 16:0/18:0. The dose of PPI-1011 was 200 mg/kg, po. N = 3 to 5 except at 12 hours (N = 7). 16:0 (palmitic acid); 18:0 (stearic acid); 18:1 (oleic acid); 22:6 (DHA).

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Lipids in Health and Disease

ISSN: 1476-511X