Time course (1 to 48 hr) of conversion of PPI-1011 to free DHA and DHA-containing plasmalogens (Pls) and phosphatidylethanolamines (Ptd). Plasma levels are normalized to levels of the housekeeping metabolite PtdEtn 16:0/18:0. The dose of PPI-1011 was 200 mg/kg, po. N = 3 to 5 except at 12 hours (N = 7). 16:0 (palmitic acid); 18:0 (stearic acid); 18:1 (oleic acid); 22:6 (DHA).