Skip to main content
Figure 3 | Lipids in Health and Disease

Figure 3

From: M2 macrophages exhibit higher sensitivity to oxLDL-induced lipotoxicity than other monocyte/macrophage subtypes

Figure 3

oxLDL-induced XBP-1 Activation in THP1-derived monocyte-macrophage cell-types. Representative images (insets) and densitometric summaries from agarose gels used to determine XBP-1 activation in THP1-Mon (A), THP1-M2Mon (B), dTHP1-MΦ (C) and dTHP1-M2MΦ (D) after treatment with oxLDL (1 μg/ml or 40 μg/ml; 24 h) or thapsigargin (100 nM; 24 h) as indicated. n ≥ 3 in all cases; P < 0.05 where indicated.

Back to article page

Lipids in Health and Disease

ISSN: 1476-511X