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Figure 3 | Lipids in Health and Disease

Figure 3

From: Thymoquinone decreases F-actin polymerization and the proliferation of human multiple myeloma cells by suppressing STAT3 phosphorylation and Bcl2/Bcl-XL expression

Figure 3

TQ diminishes IL-6-induced proliferation of MM cells. The ability of MDN (A, B, C) and XG2 (A, E, F) cells to proliferate in the presence or absence of TQ was evaluated using CFSE assays and flow cytometry. CFSE-labeled cells were then left untreated (medium-treated cells) (A, D) or treated with TQ (B, E). One representative experiment of five showing that histograms were gated on viable cells, and the mean of the left histograms represents the percentage of CFSE-lo (proliferating) cells. Combined data from 5 different experiments are expressed as the mean percentage of proliferating MDN (C) and XG2 (F) cells ± SEM, * p < 0.05.

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