Skip to main content
Figure 4 | Lipids in Health and Disease

Figure 4

From: Thymoquinone decreases F-actin polymerization and the proliferation of human multiple myeloma cells by suppressing STAT3 phosphorylation and Bcl2/Bcl-XL expression

Figure 4

Flow cytometry quantification of phospho-STAT3, phospho-STAT5 and expression of Bcl-2/Bcl- XL after TQ treatment. Phosphorylation of STAT3 (A) and STAT5 (B) as well as the anti-apoptotic molecules Bcl-2 (C) and Bcl-XL (D) in MDN (left panel) and XG2 (right panel) cells were monitored after 12-hr incubation in the presence or absence of TQ using Phosflow mAbs and flow cytometric analysis. Histograms for medium-treated cells are displayed as open bold line histograms, as gray-filled histograms in TQ-treated cells, while the isotype controls are represented by open dotted thin line histograms. One representative experiment of three in shown.

Back to article page

Lipids in Health and Disease

ISSN: 1476-511X