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Table 1 Effect of krill oil on heart and lung weights and cardiac structure and function at baseline (before MI) and 1 and 8 weeks after induction of MI

From: Krill oil attenuates left ventricular dilatation after myocardial infarction in rats

  

Control feed

Krill oil feed

  

Sham

MI

MI-nPT

MI-PT

Baseline:

BW (g)

273 ± 3

261 ± 3#

271 ± 2

270 ± 2*

1 week:

LVEDD (mm)

5.0 ± 0.2

8.1 ± 0.2###

7.9 ± 0.2

8.3 ± 0.2

 

PWT (mm)

2.4 ± 0.1

2.2 ± 0.1#

2.3 ± 0.1

2.2 ± 0.1

 

FS (%)

68 ± 2

21 ± 1###

22 ± 1

21 ± 1

 

RWT

2.5 ± 0.1

2.2 ± 0.1###

2.3 ± 0.2

2.2 ± 0.1

8 weeks:

BW (g)

427 ± 7

397 ± 9#

427 ± 8*

425 ± 6*

 

TL (mm)

38 ± 0.2

38 ± 0.4

38 ± 0.2

38 ± 0.3

 

HW/BW (mg/g)

2.7 ± 0.2

3.7 ± 0.2##

3.6 ± 0.2

3.1 ± 0.1*

 

LW/BW (mg/g)

3.2 ± 0.1

6.2 ± 0.5##

6.3 ± 0.7

4.3 ± 0.5**

 

LVEDD (mm)

6.0 ± 0.2

10.5 ± 0.3###

11.1 ± 0.3

9.8 ± 0.3††

 

PWT (mm)

3.1 ± 0.2

2.3 ± 0.1##

2.3 ± 0.1

2.4 ± 0.1

 

FS (%)

69 ± 3

18 ± 1###

16 ± 1

18 ± 1

 

RWT

3.1 ± 0.2

2.3 ± 0.1###

2.3 ± 0.1

2.4 ± 0.1

  1. MI, myocardial infarction; nPT, non-pretreated; PT, pretreated; BW, body weight; TL, tibia length; HW, hearth weight; LW, lung weight; LEVDD, left ventricular diastolic diameter; PWT, posterior wall thickness; RWT, relative wall thickness; FS, fractional shortning. Values are mean ± SEM. #P ≤ 0.05 vs sham, ##P ≤ 0.01 vs sham, ###P ≤ 0.001 vs sham, *P ≤ 0.05 vs MI-control, **P ≤ 0.01 vs MI-control, ***P ≤ 0.001 vs MI-control, P ≤ 0.05 vs MI-nPT, ††P ≤ 0.01 vs MI-nPT, †††P ≤ 0.001 sv MI-nPT.