Fatty acid distribution of cord and maternal blood in human pregnancy: special focus on individual trans fatty acids and conjugated linoleic acids

Enke, Uta; Jaudszus, Anke; Schleussner, Ekkehard; Seyfarth, Lydia; Jahreis, Gerhard; Kuhnt, Katrin

doi:10.1186/1476-511X-10-247

Table 3 Fatty acids in maternal and fetal plasma and erythrocytes (n = 55)

From: Fatty acid distribution of cord and maternal blood in human pregnancy: special focus on individual trans fatty acids and conjugated linoleic acids

	Plasma							Erythrocytes
	Mean ± SD¹ (% of total FAME)					Correlation² maternal vs. fetal		Mean ± SD¹ (% of total FAME)					Correlation² maternal vs. fetal
	maternal		fetal		P	r	P	maternal		fetal		P	r	P
C14:0	1.21	± 0.40	1.12	± 0.34		0.26		0.83	± 0.51	0.63	± 0.30	*	-0.06
C15:0	0.27	± 0.06	0.20	± 0.05		0.31	•	0.25	± 0.07	0.17	± 0.03		0.27	•
C16:0	30.2	± 2.31	29.8	± 1.40		0.15		31.8	± 2.86	34.9	± 1.62	***	0.18
C17:0	0.24	± 0.04	0.26	± 0.05		0.24		0.35	± 0.12	0.29	± 0.04		0.30	•
C18:0	5.59	± 0.78	9.99	± 0.81	***	0.12		15.1	± 1.51	15.3	± 1.18		0.01
C18:1 n-9	23.9	± 2.45	18.5	± 2.01	***	0.35	••	17.5	± 1.10	13.8	± 1.01	***	0.16
C18:1 n-7	2.05	± 0.26	3.50	± 0.46	***	0.45	•••	1.51	± 0.16	2.73	± 0.31	***	0.42	•••
C18:2 n-6	23.5	± 3.41	10.9	± 1.59	***	0.35	••	10.5	± 1.08	4.55	± 0.52	***	0.54	•••
C18:3 n-6	0.16	± 0.06	0.30	± 0.06	***	0.32	•	0.05	± 0.03	0.05	± 0.03		-0.20
C20:3 n-6	1.55	± 0.32	3.31	± 0.59	***	0.29	•	1.92	± 0.43	3.22	± 0.50	***	0.35	••
C20:4 n-6 AA	3.83	± 0.89	11.7	± 1.94	***	0.29	•	10.6	± 2.47	15.0	± 1.42	***	0.24
C22:4 n-6	0.02	± 0.02	0.03	± 0.06		-0.05		0.03	± 0.03	0.03	± 0.06		0.07
C22:5 n-6	0.19	± 0.08	0.53	± 0.16	***	0.66	•••	0.56	± 0.23	1.08	± 0.24	***	0.60	••
C18:3 n-3	0.41	± 0.11	0.12	± 0.04	***	0.37	••	0.15	± 0.04	0.03	± 0.03	***	0.04
C20:5 n-3 EPA	0.24	± 0.10	0.25	± 0.14		0.15		0.33	± 0.16	0.13	± 0.06	***	0.32	•
C22:5 n-3	0.16	± 0.04	0.21	± 0.09	***	0.17		1.29	± 0.49	0.41	± 0.12	***	-0.02
C22:6 n-3 DHA	1.21	± 0.35	3.00	± 0.83	***	0.07		3.40	± 1.45	4.24	± 0.98	***	0.02
SFA	67.8	± 4.77	71.2	± 3.09	***	0.14		80.2	± 6.71	86.3	± 3.24	***	0.05
MUFA	29.2	± 2.93	26.1	± 2.97	***	0.30	•	19.6	± 1.25	17.2	± 1.11	***	0.16
n-6 LC-PUFA	5.59	± 1.08	15.6	± 2.14	***	0.25		13.1	± 2.71	19.4	± 1.52	***	0.14
n-3 LC-PUFA	1.61	± 0.46	3.46	± 0.99	***	0.10		5.02	± 2.04	4.79	± 1.12		0.00
C18:1 t 6/7/8	0.03	± 0.01	0.02	± 0.01	***	0.11		0.07	± 0.05	0.07	± 0.09		0.05
C18:1 t 9	0.12	± 0.02	0.10	± 0.03	***	0.24		0.15	± 0.03	0.12	± 0.12		-0.06
C18:1 t 10	0.05	± 0.02	0.03	± 0.01	***	0.19		0.07	± 0.02	0.05	± 0.08		-0.12
C18:1 t 11	0.10	± 0.05	0.05	± 0.03	***	0.51	•••	0.14	± 0.04	0.06	± 0.05	***	0.13
C18:1 t 12	0.07	± 0.02	0.03	± 0.01	***	0.29	•	0.11	± 0.03	0.04	± 0.04	***	0.11
C18:1 t 13/14	0.05	± 0.02	0.17	± 0.09	***	0.19		0.08	± 0.03	0.20	± 0.04	***	0.23
C18:1 t 15	0.03	± 0.01	0.02	± 0.01	**	0.18		0.07	± 0.02	0.03	± 0.03	***	0.16
C18:1 t 16	0.05	± 0.02	0.03	± 0.01	***	0.37	••	0.06	± 0.02	0.03	± 0.01	***	0.09
C18:2 t 9,12	0.02	± 0.02	0.03	± 0.02	***	-0.24		0.02	± 0.02	0.02	± 0.01		0.09
Total t FA	0.59	± 0.12	0.52	± 0.17	**	0.36	••	0.82	± 0.15	0.64	± 0.45	**	0.07
t 9/t 11-index	1.30	± 0.53	2.17	± 0.86	***	0.39	•••	1.11	± 0.33	2.13	± 0.64	***	0.36	••
c 9,t 11 CLA	0.20	± 0.07	0.14	± 0.04	***	0.84	•••	0.12	± 0.04	0.08	± 0.04	***	0.32	•

FAME, fatty acid methyl esters; SFA, saturated fatty acids (sum of C12:0, C14:0, C15:0, C16:0, C17:0 and C18:0); MUFA, monounsaturated fatty acids (sum of the cis isomers of C16:1, C18:1 n-9 and C18:1 n-7); n-3 and n-6 LC-PUFA, omega-3 and omega-6 long chain polyunsaturated fatty acids (sum of C20:5 n-3, C22:5 n-3, C22:6 n-3 and C20:3 n-6, C20:4 n-6, C22:4 n-6, C22:5 n-6, respectively); total t FA, total trans fatty acids (sum of C18:1 t 4, t 5, t 6/7/8, t 9, t 10, t 11, t 12, t 13/14, t 15 and t 16 as well as C18:2 t 9,12, C18:3 t 3,c 9,c 11 and C18:3 c 8,t 10,t 12).
¹ Means are significantly different between maternal and fetal lipids (paired t-Test): *P < 0.05; ** P < 0.01; *** P < 0.001.
² r = Pearson correlation coefficient between the respective fatty acid in maternal and fetal plasma or erythrocyte lipids: • P < 0.05; •• P < 0.01; ••• P < 0.001.

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