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Table 3 The genotypes of rs16996148 SNP and serum lipid levels in the Mulao and Han populations

From: Sex-specific association of rs16996148 SNP in the NCAN/CILP2/PBX4 and serum lipid levels in the Mulao and Han populations

Genotype

n

TC

(mmol/L)

TG

(mmol/L)

HDL-C

(mmol/L)

LDL-C

(mmol/L)

ApoAI

(g/L)

ApoB

(g/L)

ApoAI/

ApoB

Mulao

        

   GG

541

5.03 ± 1.35

1.07(0.84)

1.72 ± 0.44

2.94 ± 0.88

1.31 ± 0.40

0.98 ± 0.56

1.59 ± 1.01

   GT

160

4.99 ± 1.11

1.02(0.73)

1.83 ± 0.50

2.88 ± 0.91

1.37 ± 0.41

0.94 ± 0.49

1.68 ± 0.73

   TT

11

4.91 ± 0.85

1.18(0.89)

1.89 ± 0.20

2.78 ± 0.74

1.32 ± 0.47

0.93 ± 0.46

1.54 ± 0.62

   F

-

0.108

1.338

3.910

0.284

1.593

0.564

0.685

   P

-

0.897

0.512

0.020

0.752

0.204

0.569

0.505

   GG

541

5.03 ± 1.35

1.07(0.84)

1.72 ± 0.44

2.94 ± 0.88

1.31 ± 0.40

0.98 ± 0.56

1.59 ± 1.01

   GT/TT

171

4.99 ± 1.09

1.03(0.74)

1.83 ± 0.49

2.87 ± 0.90

1.37 ± 0.41

0.94 ± 0.49

1.67 ± 0.73

   F

-

0.045

-1.154

7.483

0.398

2.981

1.028

1.304

   P

-

0.832

0.248

0.006

0.528

0.085

0.311

0.254

Han

        

   GG

598

4.95 ± 0,98

1.07(0.86)

1.74 ± 0.55

2.86 ± 0.81

1.35 ± 0.26

0.85 ± 0.20

1.67 ± 0.52

   GT

128

5.28 ± 1.16

1.15(1.23)

1.76 ± 0.44

3.13 ± 0.94

1.37 ± 0.23

0.90 ± 0.21

1.59 ± 0.43

   TT

10

5.40 ± 1.38

0.84(0.49)

2.17 ± 0.41

3.05 ± 1.26

1.62 ± 0.33

0.83 ± 0.26

2.15 ± 0.79

   F

 

7.467

6.323

2.473

5.504

5.845

2.909

1.940

   P

 

0.001

0.042

0.085

0.004

0.003

0.055

0.145

   GG

598

4.95 ± 0.98

1.07(0.86)

1.74 ± 0.55

2.86 ± 0.81

1.35 ± 0.26

0.85 ± 0.20

1.67 ± 0.52

   GT/TT

138

5.29 ± 1.17

1.15(1.18)

1.79 ± 0.45

3.12 ± 0.96

1.38 ± 0.25

0.89 ± 0.21

1.63 ± 0.49

   F

-

12.684

-1.555

1.389

10.222

4.955

5.469

0.091

   P

-

0.000

0.120

0.239

0.001

0.026

0.020

0.763

Mulao/male

        

   GG

243

5.18 ± 1.50

1.15(1.07)

1.72 ± 0.45

2.96 ± 0.86

1.32 ± 0.44

1.04 ± 0.62

1.48 ± 0.65

   GT/TT

87

5.08 ± 1.64

1.08(0.86)

1.86 ± 0.58

2.84 ± 0.86

1.44 ± 0.40

0.98 ± 0.52

1.70 ± 0.77

   F

-

0.276

-0.341

7.151

1.375

7.126

0.574

9.195

   P

-

0.600

0.733

0.008

0.245

0.008

0.449

0.003

Mulao/female

        

   GG

298

4.91 ± 1.21

1.03(0.65)

1.72 ± 0.44

2.92 ± 0.89

1.31 ± 0.37

0.93 ± 0.50

1.68 ± 1.22

   GT/TT

84

4.89 ± 1.01

0.95(0.60)

1.80 ± 0.38

2.90 ± 0.95

1.29 ± 0.41

0.89 ± 0.46

1.63 ± 0.68

   F

-

0.110

-1.648

1.134

0.181

0.104

0.106

0.163

   P

-

0.740

0.099

0.288

0.671

0.747

0.745

0.686

Han/male

        

   GG

246

5.08 ± 0.90

1.14(0.92)

1.69 ± 0.42

2.90 ± 0.77

1.36 ± 0.28

0.90 ± 0.19

1.58 ± 0.47

   GT/TT

62

5.59 ± 1.12

1.71(1.61)

1.75 ± 0.45

3.26 ± 0.78

1.44 ± 0.28

0.97 ± 0.23

1.56 ± 0.46

   F

-

13.935

-2.649

2.569

8.390

7.843

4.675

0.248

   P

-

0.000

0.008

0.110

0.004

0.005

0.031

0.619

Han/female

        

   GG

352

4.86 ± 1.02

1.00(0.81)

1.78 ± 0.62

2.83 ± 0.84

1.33 ± 0.24

0.81 ± 0.20

1.74 ± 0.54

   GT/TT

76

5.05 ± 1.16

0.93(0.80)

1.81 ± 0.46

3.01 ± 1.08

1.34 ± 0.21

0.84 ± 0.18

1.69 ± 0.50

   F

-

3.262

-0.389

0.133

3.680

0.141

1.239

0.548

   P

-

0.072

0.698

0.715

0.056

0.707

0.266

0.459

  1. TC, total cholesterol; TG, triglyceride; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; ApoAI, apolipoprotein AI; ApoB, apolipoprotein B
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Lipids in Health and Disease

ISSN: 1476-511X