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Table 2 Comparison of the genotypic and allelic frequencies of LDL-R gene Ava ║ polymorphism in Bai Ku Yao and Han Chinese [n (%)]

From: Low density lipoprotein receptor gene Ava II polymorphism and serum lipid levels in the Guangxi Bai Ku Yao and Han populations

Group n Genotype Allele
   A-A- A-A+ A+A+ A- A+
Bai Ku Yao 1024 436 (42.6) 470 (45.9) 118 (11.5) 1342 (65.5) 706 (34.5)
Han Chinese 792 514 (64.9) 250 (31.6) 28 (3.5) 1278 (80.7) 306 (19.3)
x 2 - 101.118 102.054
P - 0.000 0.000
   Bai Ku Yao       
Male 468 218(46.6) 190(40.6) 60(12.8) 626(66.9) 310(33.1)
Female 556 220(39.6) 278(50.0) 58(10.4) 718(64.6) 394(35.4)
x 2 - 9.095 1.204
P - 0.011 0.272
Normal TC 882 368 (41.7) 420 (47.6) 94 (10.7) 1156 (65.5) 608 (34.5)
High TC 142 68 (47.9) 50 (35.2) 24 (16.9) 186 (65.5) 98 (34.5)
x 2 - 9.332 0.000
P - 0.009 0.990
Normal LDL-C 902 392 (43.5) 414 (45.9) 96 (10.6) 1198 (66.4) 606 (33.6)
High LDL-C 122 44 (36.1) 56 (45.9) 22 (18.0) 144 (59.0) 100 (41.0)
x 2 - 6.472 5.199
P - 0.039 0.023
   Han Chinese       
Male 330 230 (69.7) 92 (27.9) 8 (2.4) 552 (83.6) 108 (16.4)
Female 462 284 (61.5) 158 (34.2) 20 (4.3) 726 (78.6) 198 (21.4)
x 2 - 6.418 6.337
P - 0.040 0.012
Normal TC 622 412 (66.2) 190 (30.6) 20 (3.2) 1014 (81.5) 230 (18.5)
High TC 170 102 (60.0) 60 (35.3) 8 (4.7) 264 (77.6) 76 (22.4)
x 2 - 2.593 2.558
P - 0.274 0.109
Normal LDL-C 636 414 (65.1) 202 (31.8) 20 (3.1) 1030 (81.0) 242 (19.0)
High LDL-C 156 100 (64.1) 48 (30.8) 8 (5.1) 248 (79.5) 64 (20.5)
x 2 - 1.452 0.356
P - 0.484 0.550
  1. TC, total cholesterol; LDL-C, low-density lipoprotein cholesterol; Normal TC, TC ≤ 5.17 mmol/L, High TC, TC >5.17 mmol/L; Normal LDL-C, LDL-C ≤ 3.20 mmol/L, High LDL-C, LDL-C >3.20 mmol/L