Table 2 Comparison of the genotypic and allelic frequencies of LDL-R gene Ava â•‘ polymorphism in Bai Ku Yao and Han Chinese [n (%)]
Group | n | Genotype | Allele | |||
|---|---|---|---|---|---|---|
| Â | Â | A-A- | A-A+ | A+A+ | A- | A+ |
Bai Ku Yao | 1024 | 436 (42.6) | 470 (45.9) | 118 (11.5) | 1342 (65.5) | 706 (34.5) |
Han Chinese | 792 | 514 (64.9) | 250 (31.6) | 28 (3.5) | 1278 (80.7) | 306 (19.3) |
x 2 | - | 101.118 | 102.054 | |||
P | - | 0.000 | 0.000 | |||
   Bai Ku Yao |  |  |  |  |  |  |
Male | 468 | 218(46.6) | 190(40.6) | 60(12.8) | 626(66.9) | 310(33.1) |
Female | 556 | 220(39.6) | 278(50.0) | 58(10.4) | 718(64.6) | 394(35.4) |
x 2 | - | 9.095 | 1.204 | |||
P | - | 0.011 | 0.272 | |||
Normal TC | 882 | 368 (41.7) | 420 (47.6) | 94 (10.7) | 1156 (65.5) | 608 (34.5) |
High TC | 142 | 68 (47.9) | 50 (35.2) | 24 (16.9) | 186 (65.5) | 98 (34.5) |
x 2 | - | 9.332 | 0.000 | |||
P | - | 0.009 | 0.990 | |||
Normal LDL-C | 902 | 392 (43.5) | 414 (45.9) | 96 (10.6) | 1198 (66.4) | 606 (33.6) |
High LDL-C | 122 | 44 (36.1) | 56 (45.9) | 22 (18.0) | 144 (59.0) | 100 (41.0) |
x 2 | - | 6.472 | 5.199 | |||
P | - | 0.039 | 0.023 | |||
   Han Chinese |  |  |  |  |  |  |
Male | 330 | 230 (69.7) | 92 (27.9) | 8 (2.4) | 552 (83.6) | 108 (16.4) |
Female | 462 | 284 (61.5) | 158 (34.2) | 20 (4.3) | 726 (78.6) | 198 (21.4) |
x 2 | - | 6.418 | 6.337 | |||
P | - | 0.040 | 0.012 | |||
Normal TC | 622 | 412 (66.2) | 190 (30.6) | 20 (3.2) | 1014 (81.5) | 230 (18.5) |
High TC | 170 | 102 (60.0) | 60 (35.3) | 8 (4.7) | 264 (77.6) | 76 (22.4) |
x 2 | - | 2.593 | 2.558 | |||
P | - | 0.274 | 0.109 | |||
Normal LDL-C | 636 | 414 (65.1) | 202 (31.8) | 20 (3.1) | 1030 (81.0) | 242 (19.0) |
High LDL-C | 156 | 100 (64.1) | 48 (30.8) | 8 (5.1) | 248 (79.5) | 64 (20.5) |
x 2 | - | 1.452 | 0.356 | |||
P | - | 0.484 | 0.550 | |||