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Table 3 Comparison of serum lipid levels among the genotypes of LDL-R gene Ava â•‘ polymorphism in Bai Ku Yao and Han Chinese

From: Low density lipoprotein receptor gene Ava II polymorphism and serum lipid levels in the Guangxi Bai Ku Yao and Han populations

Genotype

n

TC (mmol/L)

TG (mmol/L)

HDL-C (mmol/L)

LDL-C (mmol/L)

ApoAI (g/L)

ApoB (g/L)

Bai Ku Yao

       

   A-A-

436

4.23 ± 0.98

1.26 ± 0.82

1.58 ± 0.42

2.44 ± 0.69

1.24 ± 0.33

0.82 ± 0.23

   A-A+

470

4.14 ± 0.81

1.19 ± 0.79

1.56 ± 0.40

2.45 ± 0.65

1.22 ± 0.31

0.81 ± 0.24

   A+A+

118

4.38 ± 0.86c

1.27 ± 0.73

1.66 ± 0.49

2.71 ± 1.12bd

1.28 ± 0.33

0.86 ± 0.24

   F

-

3.673

1.050

2.676

6.792

1.724

2.122

   P

-

0.026

0.350

0.069

0.001

0.179

0.120

   Male

       

A-A-

218

4.17 ± 1.16

1.36 ± 1.00

1.57 ± 0.45

2.34 ± 0.80

1.25 ± 0.38

0.75 ± 0.27

A-A+

190

4.05 ± 0.90

1.28 ± 1.00

1.56 ± 0.50

2.32 ± 0.70

1.23 ± 0.40

0.75 ± 0.23

A+A+

60

4.23 ± 0.86

1.30 ± 0.79

1.62 ± 0.53

2.69 ± 1.45bc

1.27 ± 0.36

0.82 ± 0.29

F

-

1.030

0.355

0.359

4.443

0.287

1.936

P

-

0.358

0.123

0.699

0.012

0.751

0.146

   Female

       

A-A-

220

4.28 ± 0.77

1.17 ± 0.58

1.59 ± 0.38

2.55 ± 0.53

1.23 ± 0.28

0.86 ± 0.18

A-A+

278

4.20 ± 0.75

1.13 ± 0.62

1.56 ± 0.31

2.53 ± 0.60

1.21 ± 0.23

0.85 ± 0.23

A+A+

58

4.53 ± 0.84ad

1.23 ± 0.69

1.70 ± 0.45ac

2.73 ± 0.64

1.30 ± 0.31

0.90 ± 0.17

F

-

4.494

0.732

3.746

2.917

2.901

1.420

P

-

0.012

0.482

0.024

0.055

0.056

0.243

Han Chinese

       

   A-A-

514

4.49 ± 1.02

1.23 ± 0.87

1.70 ± 0.47

2.63 ± 0.82

1.34 ± 0.34

0.79 ± 0.21

   A-A+

250

4.56 ± 0.94

1.31 ± 0.99

1.78 ± 0.50

2.63 ± 0.76

1.35 ± 0.38

0.79 ± 0.20

   A+A+

28

4.44 ± 1.08

1.17 ± 1.08

2.14 ± 0.54bd

2.60 ± 0.77

1.40 ± 0.45

0.79 ± 0.23

   F

-

0.486

0.759

12.262

0.018

0.407

0.004

   P

-

0.615

0.469

0.000

0.982

0.666

0.996

   Male

       

A-A-

230

4.45 ± 0.94

1.35 ± 1.13

1.62 ± 0.48

2.64 ± 0.75

1.30 ± 0.37

0.80 ± 0.21

A-A+

92

4.45 ± 0.93

1.50 ± 1.28

1.73 ± 0.44

2.54 ± 0.82

1.33 ± 0.39

0.76 ± 0.20

A+A+

8

3.80 ± 1.45

1.56 ± 1.78

1.77 ± 0.46

2.17 ± 0.92

1.02 ± 0.21

0.66 ± 0.21

F

-

1.823

0.598

2.059

1.818

2.549

2.725

P

-

0.163

0.550

0.129

0.164

0.080

0.067

   Female

       

A-A-

284

4.53 ± 1.09

1.13 ± 0.56

1.76 ± 0.45

2.62 ± 0.87

1.36 ± 0.32

0.78 ± 0.22

A-A+

158

4.62 ± 0.95

1.20 ± 0.76

1.82 ± 0.54

2.69 ± 0.72

1.37 ± 0.38

0.81 ± 0.20

A+A+

20

4.79 ± 0.66

0.95 ± 0.38

2.35 ± 0.49

2.83 ± 0.61

1.56 ± 0.42ac

0.87 ± 0.70

F

-

0.857

1.640

13.965

0.874

3.123

1.658

P

-

0.425

0.195

0.000

0.418

0.045

0.192

  1. TC, total cholesterol; TG, triglycerides; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; ApoAI, apolipoprotein AI; ApoB, apolipoprotein B; aP < 0.05 and bP < 0.01 in comparison with A-A- genotype of same group; cP < 0.05 and dP < 0.01 in comparison with A-A+ genotype of same group.
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Lipids in Health and Disease

ISSN: 1476-511X