Table 5 Microarray analyses of RNA of livers of chickens after treatment with various compounds.
Genes up-regulated by the first four lipid-lowering compounds and lipid-raising dexamethasone | ||||||||
|---|---|---|---|---|---|---|---|---|
# | Genes | Control | δ-T3 | Quer | Ribo | Co lac | Dexa | Description |
1 | BX275358 | 3.42 | 6.22 | 6.09 | 6.66 | 5.39 | 3.31 | Putative ISG 12-2 protein |
2 | BU235638 | 1.54 | 3.51 | 5.21 | 4.32 | 4.21 | 2.15 | Similar to serine hydroxymethyltransferase 1 (soluble) |
3 | ENSGL T6 | 3.98 | 6.05 | 6.93 | 5.53 | 7.15 | 4.59 | UDP glucuronosyltransferase 1 family, polypeptide A10 |
4 | CF256116 | 1.85 | 3.58 | 4.64 | 3.76 | 4.57 | 1.91 | Phosphoribosyl pyrophosphate amidotransferase |
5 | NM_204858 | -0.48 | 0.95 | 2.05 | 1.49 | 1.70 | -0.13 | Interferon (alpha, beta, and omega) receptor 2 |
6 | AY534896 | 6.19 | 8.22 | 8.56 | 8.00 | 7.91 | 6.40 | Gal 10 |
7 | JO4598 | 0.85 | 2.79 | 3.69 | 1.89 | 3.15 | 1.32 | Collagen, type IV, alpha 1 |
8 | ENSGALT2 | 6.32 | 8.29 | 8.95 | 7.64 | 8.48 | 6.78 | Similar to inter-alpha (globulin) inhibitor H3 |
9 | ENSGALT27 | 0.84 | 3.10 | 3.18 | 2.23 | 2.50 | 0.87 | Similar to KDEL (Lys-Asp-Glu-Leu) containing 1 |
10 | M60069 | 6.14 | 8.06 | 6.71 | 7.57 | 7.88 | 6.00 | Phosphoribosyl pyrophosphate amidotransferase |
11 | ENSGALT15 | 4.35 | 5.38 | 7.00 | 5.96 | 6.71 | 4.52 | Similar to MGC 107895 protein |
12 | BX275222 | 0.23 | 2.43 | 2.64 | 1.24 | 1.59 | 0.19 | Hypothetical protein LOC69044 |
13 | ENSGALT27 | 4.80 | 6.48 | 7.13 | 5.83 | 6.84 | 5.06 | Similar to thrombin-activatable fibrinosis inhibitor |
14 | BU219227 | 1.60 | 2.82 | 4.09 | 3.16 | 3.21 | 1.92 | WD repeat domain 61 |
15 | NM_205299 | 2.29 | 3.38 | 4.62 | 3.39 | 3.66 | 2.33 | Dystrophin |
16 | ENSGALT26 | 2.10 | 3.46 | 4.27 | 3.23 | 3.67 | 2.66 | Similar to methylmalonyl coenzyme A mutase |
17 | NM_205355 | 4.83 | 6.24 | 7.15 | 5.98 | 6.12 | 5.21 | Ring finger protein 13 |
18 | ENSGALT3 | 3.62 | 4.91 | 5.89 | 4.33 | 6.40 | 3.78 | Similar to complement regulator factor H |
19 | CR290617 | 3.27 | 4.77 | 5.74 | 4.17 | 4.96 | 3.41 | RER1 retention in endoplasmic reticulum 1 homolog |
20 | ENSGALT4 | 0.99 | 2.51 | 3.36 | 1.79 | 2.62 | 1.12 | Similar to U1 snRNP-specific protein C |
21 | AF082666 | 1.22 | 1.89 | 3.24 | 1.92 | 1.86 | 1.01 | Interleukin 10 receptor, beta |
Genes down-regulated by the first four lipid-lowering compounds except dexamethasone | ||||||||
# | Genes | Control | δ-T3 | Quer | Ribo | Co lac | Dexa | Description |
1 | ENSGALT20 | 2.01 | 1.14 | -0.34 | 1.29 | 0.73 | 2.35 | Similar to Trans-Golgi p230 |
2 | BU270035 | 2.54 | 1.06 | 1.03 | -0.08 | 1.25 | 2.59 | Similar to Expressed soquence A1314180 |
3 | BU208119 | 3.84 | 3.14 | 1.33 | 2.13 | 1.93 | 3.51 | Similar to RIKEN cDNA D130059P03 gene |
4 | BU229724 | 5.44 | 3.99 | 2.96 | 3.49 | 3.57 | 5.55 | Finshed cDNA, clone Chest295h22 |
5 | ENSGALT9 | 1.84 | -0.43 | -0.23 | 0.75 | -0.57 | 2.50 | Similar to KIAA07 protein |
6 | BU305188 | 6.08 | 4.75 | 3.02 | 4.19 | 3.99 | 5.71 | PCF11, cleavage and polyadenylation factor subunit |
7 | BU426927 | 3.76 | 2.44 | -0.14 | 1.83 | 0.97 | 3.63 | Triple functional domain (PTPRF interacting) |