Antibacterial properties of chicken intestinal phospholipase A2

Table 1 Inhibitory spectrum of ChPLA2-IIA on several Gram-positive and gram-negative bacteria.

Bacteria stain	Gram	Sensitivity	IC50 (μg/ml)
Bacillus cereus	+	+++	12
Bacillus subtilis	+	+++	9.5
Micrococcus luteus	+	+++	9
Brevibacterium flavum	+	++	14
Enterococcus faecium	+	++	-
Enterococcus faecalis	+	+	34
Staphylococcus aureus	+	+	19
Staphilococcus epidermidis	+	+	14
Enterobacter cloacae	-	-	-
Klebsielle pneumoniae	-	-	-
Escherchia coli	-	-	-
Salmonella	-	-	-
Pseudomonas aeruginosa	-	-	-

The bactericidal level was estimated by measuring the size of inhibition zone of the indicator strain. Inhibitory concentration reducing 50% the bacterial growth of gram(+) bacteria.
Insensitivity (-), low sensitivity (+: Diameter of inhibition < 15 mm), high sensitivity (++: Diameter of inhibition between 15 et 20 mm) and very high sensitivity (+++: Diameter of inhibition > 20 mm).

ISSN: 1476-511X