Skip to main content

Table 5 APOA1 SNPs Association with Metabolic Syndrome (n = 94)

From: Metabolic syndrome in South Asian immigrants: more than low HDL requiring aggressive management

APOA1 Gene Polymorphisms Metabolic Syndrome
  Absent Present
G1 P319(T319C) WT 36 (42.5%) 13 (15.3%)
  Heterozygous 25 (29.4%) 4 (4.7%)
  Mutant 3 (3.5%) 4 (4.7%)
  P-value$ 0.940
G2 P655(T655C) WT 12 (14.1%) 0 (0.0%)
  Heterozygous 22 (25.9%) 7 (8.2%)
  Mutant 29 (34.1%) 15 (17.7%)
  P-value 0.040
G3 P756(T756C) WT 12 (14.0%) 0 (0.0%)
  Heterozygous 21 (24.4%) 7 (8.1%)
  Mutant 30 (34.9%) 16 (18.6%)
  P-value 0.039
G4 P938(C938T) WT 51 (59.3%) 15 (17.4%)
  Heterozygous 12 (14.0%) 7 (8.1%)
  Mutant 0 (0.0%) 1 (1.2%)
  P-value 0.109
G5 P1001(T1001C) WT 12 (13.5%) 0 (0.0%)
  Heterozygous 27 (30.3%) 11 (12.4%)
  Mutant 25 (28.1%) 15 (16.9%)
  P-value 0.054
G6 P1149(C1149T) WT 59 (66.3%) 23 (25.8%)
  Heterozygous 5 (5.6%) 2 (2.3%)
  Mutant 0 (0.0%) 0 (0.0%)
  P-value 0.976
  1. APOA1 = Apo lipoprotein A 1 gene, WT = Wild Type; $ P-values from the logistical regression analysis