Table 5 APOA1 SNPs Association with Metabolic Syndrome (n = 94)
From: Metabolic syndrome in South Asian immigrants: more than low HDL requiring aggressive management
APOA1 Gene Polymorphisms | Metabolic Syndrome | ||
|---|---|---|---|
Absent | Present | ||
G1 P319(T319C) | WT | 36 (42.5%) | 13 (15.3%) |
Heterozygous | 25 (29.4%) | 4 (4.7%) | |
Mutant | 3 (3.5%) | 4 (4.7%) | |
P-value$ | 0.940 | ||
G2 P655(T655C) | WT | 12 (14.1%) | 0 (0.0%) |
Heterozygous | 22 (25.9%) | 7 (8.2%) | |
Mutant | 29 (34.1%) | 15 (17.7%) | |
P-value | 0.040 | ||
G3 P756(T756C) | WT | 12 (14.0%) | 0 (0.0%) |
Heterozygous | 21 (24.4%) | 7 (8.1%) | |
Mutant | 30 (34.9%) | 16 (18.6%) | |
P-value | 0.039 | ||
G4 P938(C938T) | WT | 51 (59.3%) | 15 (17.4%) |
Heterozygous | 12 (14.0%) | 7 (8.1%) | |
Mutant | 0 (0.0%) | 1 (1.2%) | |
P-value | 0.109 | ||
G5 P1001(T1001C) | WT | 12 (13.5%) | 0 (0.0%) |
Heterozygous | 27 (30.3%) | 11 (12.4%) | |
Mutant | 25 (28.1%) | 15 (16.9%) | |
P-value | 0.054 | ||
G6 P1149(C1149T) | WT | 59 (66.3%) | 23 (25.8%) |
Heterozygous | 5 (5.6%) | 2 (2.3%) | |
Mutant | 0 (0.0%) | 0 (0.0%) | |
P-value | 0.976 | ||