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Table 7 Definition of Metabolic Syndrome (MS)

From: Metabolic syndrome in South Asian immigrants: more than low HDL requiring aggressive management

  IDF (2005) NCEP ATP III (2001) European Group (1999) WHO 1999
  Central obesity (ethnicity-specific)‡ and two or more of the following: Three or more of the following: Non-diabetics with insulin resistance§ and two or more of the following: T2 D, impaired glucose tolerance, impaired fasting glucose, or insulin resistance* plus two or more of the following:
Glucose (fasting) ≥100 mg/dL (5.6 mmol/L) or T2D ≥110 mg/dL (6.1 mmol/L)† ≥110 mg/dL (6.1 mmol/L), but non-diabetic  
Obesity Central obesity (ethnicity-specific)‡ Waist circumference ≥102 cm (40 in) in males or ≥ 88 cm (35 in) in females Waist circumference ≥ 94 cm (37.0 in) in males or ≥ 80 cm (31.5 in) in females Central obesity (WHR ≥ 0.90 in males or ≥ 0.85 in females) and/or BMI ≥ 30 kg/m2
HDL Levels ≥ 40 mg/dL (1.03 mol/L) in males, ≥ 50 mg/dL (1.29 mmol/L) in females, or treatment ≥ 40 mg/dL (1.03 mmol/L) in males or ≥ 50 mg/dL (1.29 mmol/L) in females ≥ 39 mg/dL (1.0 mmol/L) or treatment ≥ 35 mg/dL (0.9 mmol/L) in males or ≥ 39 mg/dL (≥ 1.0 mmol/L) in females
Blood Pressure ≥130/≥85 mmg or treatment ≥140/90 mm Hg or treatment ≥140/90 mm Hg or treatment ≥140/90 mm Hg
Triglycerides ≥150 mg/dL (1.7 mmol/L) or treatment ≥150 mg/dL (1.7 mmol/L) ≥150 mg/dL (1.7 mmol/L) or treatment ≥178 mg/dL (2.0 mmol/L) or treatment
  1. *Refer to WHO publication for definitions of hyperglycemic states. Insulin resistance defined as glucose uptake below lowest quartile for background population under investigation, in hyperinsulinemic, euglycemic conditions. †Revised in 2004 to ≥100 mg/dL (5.6 mmol/L) to reflect the American Diabetes Association's updated definition of
  2. impaired fasting glucose.9,132 ‡Defined as ≥ 94 cm (males) or ≥ 0 cm (females) in Europids and ≥ 90 cm (males) or ≥ 80 cm (females) in South Asians, among others. §Defined as the 25% of the non diabetic population with the highest insulin resistance or the highest fasting insulin concentrations.
  3. Abbreviations: BMI, body mass index; European group = European Group for the Study of Insulin Resistance; HDL, high-density lipoprotein; IDF, International Diabetes Federation; NCEP
  4. ATP III, National Cholesterol Education Program Adult Treatment Panel; T2 D, type II diabetes mellitus; WHO, World Health Organization; WHR, waist-to-hip ratio.