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Table 3 Baseline prior history and medication of the 455 patients with different apoE alleles

From: Apolipoprotein E epsilon-4 polymorphism is associated with younger age at referral to a lipidology clinic and a poorer response to lipid-lowering therapy

 

Total

Non-ε4 carriers

ε4 carriers

Odds-ratio (95% CI)

p-value

Prior history

     

   Diabetes mellitus

24.9%

26.3%

20.5%

0.723 (0.398-1.313)

0.285

   Prior CHD

4.2%

4.9%

2.4%

0.478 (0.105 - 2.179)

0.330

   Current smoker

21.2%

22.4%

17.1%

0.712 (0.375 - 1.353)

0.298

   Alcohol consumption

52.8%

55.1%

45.1%

0.670 (0.408 - 1.101)

0.112

   Regular exercise

10.6%

11.2%

8.4%

0.728 (0.308 - 1.720)

0.467

   Use of a salty diet

57.3%

58.2%

54.2%

0.851 (0.519 - 1.395)

0.522

Prior medication

     

   Aspirin

41.8%

44.5%

32.9%

0.612 (0.357 - 1.048)

0.072

   Beta-blockers

22.0%

23.7%

16.7%

0.646 (0.325 - 1.284)

0.210

   ACEi

33.3%

36.4%

23.0%

0.522 (0.287 - 0.950)

0.032

   ARB

21.3%

21.9%

19.2%

0.817 (0.415 - 1.607)

0.614

   Calcium antagonist

19.2%

19.9%

16.9%

0.817 (0.415 - 1.607)

0.557

   Hypolipidemic drug*

81.6%

83.1%

76.5%

0.663 (0.344 - 1.277)

0.217

  1. ACEi: angiotensin converting enzime inhibitor: ARB: angiotensin receptor blocker *Statin or fibrate.