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Table 3 Comparison of serum lipid levels among genotypes of Bai Ku Yao and Han Chinese

From: The proprotein convertase subtilisin/kexin type 9 gene E670G polymorphism and serum lipid levels in the Guangxi Bai Ku Yao and Han populations

Genotype

n

TC (mmol/L)

TG (mmol/L)

HDL-C (mmol/L)

LDL-C (mmol/L)

ApoAI (g/L)

ApoB (g/L)

ApoAI/ApoB

Bai Ku Yao

        

   AA

623

4.27 ± 0.93

0.98(0.67)

1.62 ± 0.40

2.51 ± 0.77

1.28 ± 0.31

0.83 ± 0.21

1.66 ± 0.74

   AG/GG

26

4.34 ± 1.08

1.04(0.54)

1.60 ± 0.44

2.58 ± 0.67

1.24 ± 0.35

0.83 ± 0.20

1.59 ± 0.61

   F

-

0.679

0.089

1.327

0.583

0.042

0.252

0.279

   P

-

0.410

0.642

0.250

0.445

0.839

0.616

0.597

   Male

        

AA

309

4.31 ± 1.08

1.09(0.79)

1.63 ± 0.45

2.49 ± 0.91

1.32 ± 0.37

0.82 ± 0.23

1.77 ± 0.94

AG/GG

15

4.46 ± 1.32

1.04(0.62)

1.61 ± 0.46

2.61 ± 0.72

1.26 ± 0.34

0.81 ± 0.22

1.68 ± 0.68

F

-

0.742

0.330

0.296

0.792

0.017

0.003

0.003

P

-

0.390

0.714

0.587

0.374

0.897

0.958

0.954

   Female

        

AA

314

4.23 ± 0.76

0.91(0.59)

1.62 ± 0.35

2.54 ± 0.79

1.23 ± 0.24

0.83 ± 0.19

1.56 ± 0.47

AG/GG

11

4.23 ± 0.86

1.05(0.51)

1.60 ± 0.44

2.55 ± 0.90

1.23 ± 0.38

0.85 ± 0.18

1.52 ± 0.56

F

-

0.018

0.390

0.181

0.003

0.057

0.221

0.217

P

-

0.895

0.696

0.671

0.954

0.811

0.639

0.641

Han Chinese

        

   AA

588

4.61 ± 1.08

1.01(0.77)

1.74 ± 0.47

2.63 ± 0.82

1.35 ± 0.31

0.84 ± 0.23

1.70 ± 0.59

   AG/GG

58

4.79 ± 0.91

1.10(0.66)

1.86 ± 0.55

2.74 ± 0.80

1.41 ± 0.33

0.83 ± 0.26

1.87 ± 0.77

   F

-

0.607

0.089

3.959

0.332

2.165

0.650

5.394

   P

-

0.436

0.929

0.047

0.565

0.142

0.420

0.021

   Male

        

AA

288

4.53 ± 1.07

1.08(0.90)

1.66 ± 0.43

2.58 ± 0.82

1.30 ± 0.29

0.83 ± 0.24

1.68 ± 0.65

AG/GG

32

5.13 ± 0.79

1.13(0.80)

1.86 ± 0.57

2.98 ± 0.65

1.47 ± 0.33

0.94 ± 0.25

1.74 ± 0.82

F

-

2.654

0.713

4.365

2.075

4.825

1.464

0.191

P

-

0.104

0.476

0.037

0.151

0.029

0.227

0.663

   Female

        

AA

300

4.69 ± 1.07

0.96(0.68)

1.82 ± 0.48

2.71 ± 0.82

1.39 ± 0.32

0.85 ± 0.22

1.72 ± 0.53

AG/GG

26

4.51 ± 0.92

0.97(0.57)

1.87 ± 0.54

2.56 ± 0.86

1.36 ± 0.31

0.74 ± 0.23

1.97 ± 0.72

F

-

0.138

0.190

1.235

0.178

0.130

4.412

6.655

P

-

0.710

0.850

0.267

0.674

0.719

0.036

0.010

  1. TC, total cholesterol; TG, triglycerides; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; ApoAI, apolipoprotein AI; ApoB, apolipoprotein B; ApoAI/ApoB, the ratio of apolipoprotein AI to apolipoprotein B. The value of TG was presented as median (interquartile range). The difference between the genotypes was determined by the Wilcoxon-Mann-Whitney test.