The proprotein convertase subtilisin/kexin type 9 gene E670G polymorphism and serum lipid levels in the Guangxi Bai Ku Yao and Han populations

Aung, Lynn Htet Htet; Yin, Rui-Xing; Miao, Lin; Hu, Xi-Jiang; Yan, Ting-Ting; Cao, Xiao-Li; Wu, Dong-Feng; Li, Qing; Pan, Shang-Ling; Wu, Jin-Zhen

doi:10.1186/1476-511X-10-5

Lipids in Health and Disease

Table 4 Correlative factors for serum lipid parameters between Bai Ku Yao and Han Chinese

From: The proprotein convertase subtilisin/kexin type 9 gene E670G polymorphism and serum lipid levels in the Guangxi Bai Ku Yao and Han populations

Lipid parameter	Relative factor	Unstandardized coefficient	Std. error	Standardized coefficient	t	P
Bai plus Han
TC	Diastolic blood pressure	0.020	0.003	0.205	7.026	0.000
	Body mass index	0.060	0.009	0.190	6.812	0.000
	Age	0.108	0.017	0.180	6.544	0.000
	Sex	0.115	0.053	0.058	2.171	0.030
	Ethnic group	-0.332	0.052	-0.163	-6.355	0.000
TG	Body mass index	0.063	0.011	0.162	5.599	0.000
	Sex	-0.236	0.073	-0.097	-3.208	0.001
	Alcohol consumption	0.146	0.047	0.094	3.129	0.002
	Ethnic group	-0.144	0.065	-0.060	-2.217	0.027
HDL-C	Age	0.064	0.008	0.237	8.187	0.000
	Ethnic group	-0.128	0.024	-0.144	-5.295	0.000
	Body mass index	-0.019	0.004	-0.132	-4.561	0.000
	Sex	0.137	0.027	0.155	5.101	0.000
	Alcohol consumption	0.077	0.017	0.136	4.463	0.000
	Genotype	0.126	0.049	0.069	2.554	0.011
	Diastolic blood pressure	0.003	0.001	0.066	2.189	0.029
LDL-C	Body mass index	0.055	0.007	0.226	8.042	0.000
	Age	0.079	0.013	0.171	6.087	0.000
	Diastolic blood pressure	0.011	0.002	0.149	5.138	0.000
	Alcohol consumption	-0.132	0.026	-0.136	-4.978	0.000
	Ethnic group	-0.107	0.042	-0.067	-2.528	0.012
ApoAI	Age	0.050	0.006	0.267	8.814	0.000
	Alcohol consumption	0.074	0.012	0.186	6.273	0.000
	Sex	0.056	0.018	0.091	3.093	0.002
	Ethnic group	-0.078	0.017	0.123	-4.651	0.000
	Diastolic blood pressure	0.001	0.001	0.079	2.629	0.009
ApoB	Body mass index	0.017	0.002	0.243	8.716	0.000
	Systolic Blood pressure	0.004	0.001	0.176	6.041	0.000
	Age	0.020	0.004	0.148	5.392	0.000
Bai Ku Yao
TC	Body mass index	0.076	0.014	0.211	5.273	0.000
	Sex	0.081	0.024	0.140	3.431	0.000
	Systolic blood pressure	0.008	0.004	0.088	2.139	0.033
TG	Sex	-0.478	0.118	-0.211	-4.060	0.001
	Body mass index	0.069	0.020	0.141	3.498	0.001
	Alcohol consumption	0.176	0.063	0.133	2.816	0.005
	Cigarette smoking	-0.179	0.073	-0.128	-2.455	0.014
HDL-C	Age	0.052	0.011	0.192	4.622	0.000
	Alcohol consumption	0.077	0.022	0.169	3.580	0.000
	Sex	0.071	0.036	0.091	1.998	0.046
LDL-C	Body mass index	0.066	0.012	0.223	5.560	0.000
	Sex	0.064	0.020	0.137	3.264	0.001
	Alcohol consumption	-0.107	0.033	-0.135	-3.272	0.001
	Diastolic blood pressure	0.007	0.003	0.091	2.192	0.029
ApoAI	Alcohol consumption	0.090	0.014	0.253	6.313	0.000
	Age	0.040	0.008	0.192	4.783	0.000
ApoB	Body mass index	0.019	0.004	0.217	5.374	0.000
	Age	0.017	0.006	0.117	2.772	0.006
	Diastolic blood pressure	0.002	0.001	0.095	2.286	0.023
	Alcohol consumption	-0.023	0.010	-0.094	-2.266	0.024
ApoAI/ApoB	Sex	-0.234	0.060	-0.150	-3.903	0.000
	Body mass index	-0.042	0.013	-0.122	-3.143	0.002
	Age	0.057	0.021	0.106	2.738	0.006
Han Chinese
TC	Diastolic blood pressure	0.028	0.004	0.283	7.042	0.000
	Age	0.111	0.022	0.186	4.95	0.000
	Body mass index	0.050	0.011	0.172	4.464	0.000
	Sex	0.354	0.088	0.165	4.022	0.000
	Cigarette smoking	0.110	0.053	0.086	2.082	0.038
TG	Diastolic blood pressure	0.020	0.005	0.176	4.174	0.000
	Body mass index	0.059	0.014	0.171	4.181	0.000
	Cigarette smoking	0.148	0.063	0.097	2.357	0.019
	Alcohol consumption	0.156	0.076	0.085	2.045	0.041
HDL-C	Age	0.067	0.011	0.253	6.404	0.000
	Sex	0.216	0.038	0.226	5.605	0.000
	Alcohol consumption	0.104	0.028	0.151	3.746	0.000
	Body mass index	-0.024	0.005	-0.187	-4.586	0.000
	Diastolic blood pressure	0.005	0.002	0.114	2.662	0.008
	Genotype	0.148	0.062	0.088	2.384	0.017
LDL-C	Body mass index	0.050	0.009	0.224	5.616	0.000
	Age	0.077	0.018	0.170	4.379	0.000
	Diastolic blood pressure	0.015	0.003	0.200	4.813	0.000
	Alcohol consumption	-0.128	0.048	-0.108	-2.67	0.008
	Sex	0.200	0.071	0.122	2.835	0.005
	Cigarette smoking	0.088	0.043	0.09	2.053	0.040
ApoAI	Age	0.058	0.007	0.336	8.923	0.000
	Sex	0.131	0.024	0.211	5.458	0.000
	Alcohol consumption	0.075	0.017	0.168	4.333	0.000
	Diastolic blood pressure	0.003	0.001	0.113	2.940	0.003
ApoB	Body mass index	0.016	0.002	0.247	6.400	0.000
	Diastolic blood pressure	0.005	0.001	0.220	5.633	0.000
	Age	0.025	0.005	0.188	5.082	0.000
ApoAI/ApoB	Body mass index	-0.043	0.007	-0.256	-6.491	0.000
	Age	0.045	0.013	0.133	3.384	0.001

TC, total cholesterol; TG, triglyceride; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; ApoAI, apolipoprotein AI; ApoB, apolipoprotein B.

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ISSN: 1476-511X

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