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Table 2 FVII genotype polymorphisms of FH and control patients

From: R353Q polymorphism in the factor VII gene and cardiovascular risk in Heterozygous Familial Hypercholesterolemia: a case-control study

  Controls N = 174 Familiar hypercholesterolemia N = 546 Total N = 720 Value of P*
Genotype
R353Q FVII
    0.32
RR 131 (75.3%) 410 (75.1%) 541 (75.1%)  
RQ 37 (21.3%) 127 (23.3%) 164 (22.8%)  
QQ 6 (3.4%) 9 (1.6%) 15 (2.1%)  
     0.96
RR 131 (75.3%) 410 (75.1%) 541 (75.1%)  
RQ/QQ 43 (24.7%) 136 (24.9%) 179 (24.9%)  
Allele frequency     
R 0.86 (0.82-0.89) 0.87 (0.85-0.89)   
Q 0.14 (0.11-0.18) 0.13 (0.11-0.15)   
  1. *P values expressed by χ2 (Pearson). FVII: Factor VII.