R353Q polymorphism in the factor VII gene and cardiovascular risk in Heterozygous Familial Hypercholesterolemia: a case-control study

Table 4 FVII Ag levels in controls and FH patients

		Controls (n = 160)	Familiar hypercholesterolemia (n = 160)
Genotype R353Q FVII	FVII levels (ng/mL)
RR (n = 120)	Mean	374.6 ± 239.6	292.8 ± 157.6
	Adjusted mean	372.9 ± 204.7	288.6 ± 211.2
RQ/QQ (n = 40)	Mean	387.5 ± 248.2	265.6 ± 130.8
	Adjusted mean	376.7 ± 198.1	293.9 ± 200.2

Values expressed as means ± standard deviation. Analysis of variance for two factors (FH and genotype) adjusted for age, sex, diabetes, smoking, arterial hypertension and cardiovascular disease. No differences were found for the interaction between both factors (0.96). FVII: Factor VII.

ISSN: 1476-511X