Table 7 Effect of osmotic pressure on release of NP and MP from CF6
Time (h) | Cumulative % of drug release | |||||||
|---|---|---|---|---|---|---|---|---|
| Â | NP | MP | ||||||
| Â | CF6 | 7.8 atm | 13.85 atm | 21.27 atm | CF6 | 7.8 atm | 13.85 atm | 21.27 atm |
0 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
2 | 13.28 | 8.50 | 5.20 | 3.10 | 15.31 | 10.20 | 6.21 | 3.45 |
4 | 31.81 | 24.30 | 18.40 | 12.30 | 31.71 | 24.60 | 18.20 | 12.00 |
6 | 44.74 | 33.20 | 30.10 | 22.40 | 45.66 | 38.60 | 29.50 | 21.40 |
8 | 59.28 | 48.40 | 41.50 | 29.50 | 59.41 | 50.00 | 39.50 | 30.20 |
10 | 73.15 | 65.00 | 56.40 | 45.30 | 75.27 | 66.14 | 58.70 | 50.36 |
12 | 88.14 | 79.10 | 68.00 | 58.60 | 89.13 | 79.50 | 70.13 | 64.20 |