Lipids in Health and Disease

Table 7 Levels of proteins involved in adipose tissue lipid uptake and mobilization

From: Isocaloric intake of a high-fat diet modifies adiposity and lipid handling in a sex dependent manner in rats

	Male		Female
	Control	HF	Control	HF	ANOVA
Gonadal fat
CPT1	100 ± 18	55.2 ± 2.1^a	83.4 ± 8.0	64.6 ± 12	D
LPL	100 ± 8	89.8 ± 13.8	71.4 ± 10.6	84.4 ± 12.1	NS
HSL	100 ± 14	58.4 ± 11.0	135 ± 17	154 ± 32^b	S
PKA	100 ± 8	131 ± 17	90.9 ± 8.2	131 ± 16^a	D
α2-AR	100 ± 7	103 ± 4	132 ± 7^b	99.8 ± 12.8^a	SxD
β3-AR	100 ± 12	127 ± 8^a	137 ± 9^b	155 ± 5^b	S, D
α2/β3- AR	1.05 ± 0.11	0.82 ± 0.05^a	0.97 ± 0.06	0.64 ± 0.06^a	D
Inguinal fat
CPT1	100 ± 23	34.8 ± 7.6^a	39.6 ± 11.4^b	24.2 ± 7.6	S, D
LPL	100 ± 23	344 ± 35^a	204 ± 36^b	133 ± 36^b	D, SxD
HSL	100 ± 37	88.8 ± 32.0	97.0 ± 15.4	98.7 ± 37.6	NS
PKA	100 ± 27	100 ± 12	105 ± 16	97 ± 18	NS
α2-AR	100 ± 4	89.0 ± 3.1	72.9 ± 7.7^b	75.6 ± 10.3	S
β3-AR	100 ± 10	94.5 ± 5.7	110 ± 9	84.3 ± 5.5	NS
α2/β3- AR	1.03 ± 0.08	0.98 ± 0.07	0.81 ± 0.15	0.91 ± 0.11	NS

Values are expressed in arbitrary units (AU). Mean values of control male rat were set as 100%. Values are expressed as the mean ± S.E.M. of 7 animals per group. ANOVA (p < 0.05): S, sex effect; D, diet effect; SxD, interactive effect; NS, non significant; Student's t-test (p < 0.05): ^aHF vs Control, ^bFemale vs Male.

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