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Table 1 Characteristics of the patients and healthy subjects

From: Impaired lipid metabolism in idiopathic pulmonary alveolar proteinosis

 

Control

(n = 157)

Patients

(n = 33)

P

Sex (male/female)

84/73

23/10

0.088

Mean age (yrs)

41 ± 12

44 ± 9

0.195

BMI (kg/m2)

24.6 ± 3.6

23.7 ± 3.7

0.223

Cardiovascular history

19/144 (13.2%)

7/33 (21.2%)

0.368

Smoking status:yes/total (%)

48/144 (33.3%)

15/33 (45.5%)

0.19

Systolic blood pressure (mmHg)

122 ± 14

121 ± 18

0.817

Diastolic blood pressure (mmHg)

78 ± 10

79 ± 13

0.727

Fasting serum glucose (mmol/l)

4.67 ± 0.44

4.66 ± 0.64

0.936

TC (mg/dl)

191.24 ± 35.60

198.87 ± 43.16

0.283

TG (mg/dl)*

118.65(78.81-193.03)

192.00(104.36-219.00)

0.011

HDL-C (mg/dl)

51.34 ± 12.06

42.56 ± 10.30

<0.001

LDL-C (mg/dl)

119.56 ± 32.04

133.41 ± 35.54

0.03

LDL/HDL

2.46 ± 0.87

3.30 ± 1.17

<0.001

TG/HDL

3.28 ± 2.88

4.75 ± 3.11

0.001

TC/HDL

3.90 ± 1.05

4.89 ± 1.41

<0.001

Hb (g/L)

145.28 ± 15.01

158.85 ± 22.66

<0.001

FEV1 pred (%)

93.74 ± 13.33

76.79 ± 19.28

<0.001

FVC pred (%)

96.80 ± 12.37

75.98 ± 19.97

<0.001

FEV1/FVC (%)

83.12 ± 6.74

83.54 ± 6.53

0.757

  1. Values are expressed as the mean ± SD unless otherwise indicated. *: Values are expressed as median, 25% and 75%. Nonparametric Mann-Whitney U-test was used, as data were not normally distributed.