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Table 1 Effects of tocols on hematocrit levels, and the number of platelets in whole blood and in platelet rich plasma in stenosed canine arteries

From: Tocotrienols-induced inhibition of platelet thrombus formation and platelet aggregation in stenosed canine coronary arteries

  Hematocrit1
Dogs Pre-dose Post-dose
α-Tocopherol 47.97% ± 6.36 (100)4 48.33% ± 0.64 (101)
α-Tocotrienol 49.47% ± 1.87 (100) 46.40% ± 2.99 (94)
TRF3 46.45% ± 5.84 (100) 41.45% ± 7.01 (89)
  Platelet Counts in Whole Blood 2
Dogs Pre-dose Post-dose
α-Tocopherol 234.83 ± 42.09 (100)4 188.33 ± 54.47 (80)
α-Tocotrienol 262.67 ± 49.61 (100) 188.00 ± 36.23 (72)
TRF3 280.38 ± 63.25 (100) 207.25 ± 43.25 (74)
  Platelet Counts in Platelet Rich Plasma 1
Dogs Pre-dose Post-dose
α-Tocopherol 196.00 ± 6.93 (100)4 194.22 ± 6.00 (99)
α-Tocotrienol 187.67 ± 10.79 (100) 175.33 ± 10.79 (93)
TRF3 170.00 ± 24.49 (100) 164.75 ± 17.42 (97)
  1. 1Average of 3 or 4 treatments: α-Tocopherol (1 + 2 + 3); α-Tocotrienol
  2. (4 + 5 + 6); TRF (mixture of α-, γ-, δ-tocotrienols; 7 + 8 + 9 + 10). Reported as thousands/μl.
  3. 2Average of duplicate analyses of 3 or 4 treatments: α-Tocopherol (1 - 3);
  4. α-Tocotrienol (4 - 6); TRF (7 - 10). Reported as thousands/μl.
  5. 3TRF = tocotrienol rich fraction (α-tocotrienol + γ-tocotrienol + δ-tocotrienol)
  6. 4Percentages of pre-dose or post-dose values are in parentheses.