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Table 1 Effects of tocols on hematocrit levels, and the number of platelets in whole blood and in platelet rich plasma in stenosed canine arteries

From: Tocotrienols-induced inhibition of platelet thrombus formation and platelet aggregation in stenosed canine coronary arteries

 

Hematocrit1

Dogs

Pre-dose

Post-dose

α-Tocopherol

47.97% ± 6.36 (100)4

48.33% ± 0.64 (101)

α-Tocotrienol

49.47% ± 1.87 (100)

46.40% ± 2.99 (94)

TRF3

46.45% ± 5.84 (100)

41.45% ± 7.01 (89)

 

Platelet Counts in Whole Blood 2

Dogs

Pre-dose

Post-dose

α-Tocopherol

234.83 ± 42.09 (100)4

188.33 ± 54.47 (80)

α-Tocotrienol

262.67 ± 49.61 (100)

188.00 ± 36.23 (72)

TRF3

280.38 ± 63.25 (100)

207.25 ± 43.25 (74)

 

Platelet Counts in Platelet Rich Plasma 1

Dogs

Pre-dose

Post-dose

α-Tocopherol

196.00 ± 6.93 (100)4

194.22 ± 6.00 (99)

α-Tocotrienol

187.67 ± 10.79 (100)

175.33 ± 10.79 (93)

TRF3

170.00 ± 24.49 (100)

164.75 ± 17.42 (97)

  1. 1Average of 3 or 4 treatments: α-Tocopherol (1 + 2 + 3); α-Tocotrienol
  2. (4 + 5 + 6); TRF (mixture of α-, γ-, δ-tocotrienols; 7 + 8 + 9 + 10). Reported as thousands/μl.
  3. 2Average of duplicate analyses of 3 or 4 treatments: α-Tocopherol (1 - 3);
  4. α-Tocotrienol (4 - 6); TRF (7 - 10). Reported as thousands/μl.
  5. 3TRF = tocotrienol rich fraction (α-tocotrienol + γ-tocotrienol + δ-tocotrienol)
  6. 4Percentages of pre-dose or post-dose values are in parentheses.