Tocotrienols-induced inhibition of platelet thrombus formation and platelet aggregation in stenosed canine coronary arteries

Table 2 Effects of α-tocopherol on the concentration of tocols in canine plasma and platelets¹

Treatments	Total tocopherols (T)²	Total tocotrienols (T3)³	Total T + T3
α-Tocopherol (T)		Concentrations in μg/ml (ppm)
Plasma (Pre-dose)
Total Tocols⁴	17.60 ± 0.32 ^a (86) ⁵	2.89 ± 0.05 ^a (14)	20.49 ± 0.26 ^a (100)
Plasma (Post-dose)
Total Tocols	56.91 ± 0.18 ^b (97)	1.49 ± 0.03 ^b (3)	58.40 ± 1.65 ^b (100)
Platelets (Pre-dose)
Total Tocols	10.05 ± 0.27 ^a (80)	2.84 ± 0.02 ^a (20)	12.89 ± 0.29 ^a (100)
Platelets (Post-dose)
Total Tocols	42.22 ± 0.21 ^b (95)	2.33 ± 0.04 ^a (5)	44.55 ± 0.22 ^b (100)

¹Data expressed as means ± SD, n = 3, 3, and 4 respectively, per treatment.
²Total tocopherols = Mixture of α-tocopherol + β-tocopherol + γ-tocopherol + δ-tocopherol (T).
³Total tocotrienols = Mixture of α-tocotrienol + β-tocotrienol + γ-tocotrienol + δ-tocotrienol (T3).
⁴Tocols = Mixture of α-, β-, γ-, and δ-tocopherols (T) + α-, β-, γ-, and δ-tocotrienols (T3).
⁵Percentages of control values are in parentheses.
^a-bValues in columns with a different superscript letter are significantly different at P < 0.05.

ISSN: 1476-511X