Protective effect of Garcinia against renal oxidative stress and biomarkers induced by high fat and sucrose diet

Table 1 Effect of HFD, HSD and Garcinia treatments on kidney function and lipid profile in different groups of rats.

	Control	HFD	HFD+ G	HSD	HSD+ G
Creatinine (mg/dl)	0.3 ± 0.02^a	0.8 ± 0.03^b	0.4 ± 0.04^ac	0.8 ± 0.04^b	0.3 ± 0.04^ac
Urea (mg/dl)	19 ± 1.5 ^a	38 ± 2.4 ^b	14 ± 0.91^ac	30 ± 3.9 ^d	15 ± 1.8 ^ac
TC (mg/dl)	81 ± 1.4^a	351.01 ± 4.6^b	112 ± 1.3^c	320 ± 3.3^b	172 ± 4.5^e
TG (mg/dl)	85 ± 2.3^a	384.01 ± 11^b	203 ± 2.7^c	350 ± 3.9^bd	201 ± 10^ce
LDL (mg/dl)	26 ± 2.1^a	284 ± 5.5^b	61 ± 3^c	212 ± 4.9^d	61 ± 3.9^c
HDL (mg/dl)	44 ± 1.8^a	73 ± 2.2^a	72 ± 2.8^a	77 ± 6.5^a	66 ± 2.3^a

Each value is the mean ± SEM. Means have different superscript letters indicate significant variation at (P ≤ 0.05), while the same letters indicate non significant variation
Serum urea and creatinine levels were significantly increased in HFD and HSD compared with control group. In addition, TC, triglyceride and LDL levels were also significantly increased in group HFD and HSD compared with those in control group. HFD and HSD-administered rats with Garcinia produced significant decrease in serum urea, creatinine, TC, triglyceride and LDL levels compared to their respective HFD and HSD-treated rats.
Effect of HFD, HSD and Garcinia treatments on blood glucose, G6pD and adipose tissues during three months in different groups of rats

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