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Table 2 Effect of HFD, HSD and Garcinia treatments on blood glucose, G6pD and adipose tissues during three months in different groups of rats

From: Protective effect of Garcinia against renal oxidative stress and biomarkers induced by high fat and sucrose diet

 

Control

HFD

HFD+G

HSD

HSD+G

Glucose (mg/dl)

59.0 ± 1.6 a

111.0 ± 4.1b

91.0 ± 3.9c

71.0 ± 3.2 ad

63.0 ± 3.6 ad

G6pD (mU/ml)

0.25 ± 0.02a

0.14 ± 0.01b

0.12 ± 0.002b

0.53 ± 0.04c

0.54 ± 0.03 c

Mesenteric fat (g)

1.7 ± 0.19a

3.6 ± 0.41b

2.6 ± 0.29c

3. 2 ± 0.29c

2.2 ± 0.33 e

Perirenal fat (g)

2.4 ± 0.29a

3.3 ± 0.23b

1.3 ± 0.31ac

3.4 ± 0.2bc

2.2 ± 0.3d

Epididymal fat (g)

0.88 ± 0.06a

2.3 ± 0.075b

1.1 ± 0.041c

1.9 ± 0.025b

1.2 ± 0.1 dc

  1. Each value is the mean ± SEM. Means have different superscript letters indicate significant variation at (P ≤ 0.05), while the same letters indicate non significant variation
  2. Plasma glucose was significant increased in HFD group compared with control and these levels were significantly lowered in HFD+G than HFD group p ≤ 0.05. There were significant increases in G6pD activities in HSD and HSD+G groups p ≤ 0.05 than control, while giving Garcinia ameliorated these changes.
  3. Mesenteric, perirenal and epididymal adipose tissue weight were significantly increased in HFD and HSD compared with control group.
  4. The mesenteric, perirenal and epididymal fat-pad weights were reduced by 28%, 61% and 52% respectively in rats fed HFD+G than HFD rat (p < 0.05). While the mesenteric, perirenal and epididymal fat-pad weights were reduced by 31%, 35% and 37% respectively, in rats fed HSD+G than HSD rat. Garcinia treatment tended to decrease adipose tissues weight compared with HFD and HSD
  5. Effect of HFD, HSD and Garcinia treatments on renal catalase and both serum and renal MDA and NO levels in rats.