| Control | HFD | HFD+G | HSD | HSD+G |
---|
Glucose (mg/dl)
| 59.0 ± 1.6 a | 111.0 ± 4.1b | 91.0 ± 3.9c | 71.0 ± 3.2 ad | 63.0 ± 3.6 ad |
G6pD (mU/ml)
| 0.25 ± 0.02a | 0.14 ± 0.01b | 0.12 ± 0.002b | 0.53 ± 0.04c | 0.54 ± 0.03 c |
Mesenteric fat (g)
| 1.7 ± 0.19a | 3.6 ± 0.41b | 2.6 ± 0.29c | 3. 2 ± 0.29c | 2.2 ± 0.33 e |
Perirenal fat (g)
| 2.4 ± 0.29a | 3.3 ± 0.23b | 1.3 ± 0.31ac | 3.4 ± 0.2bc | 2.2 ± 0.3d |
Epididymal fat (g)
| 0.88 ± 0.06a | 2.3 ± 0.075b | 1.1 ± 0.041c | 1.9 ± 0.025b |
1.2 ± 0.1
dc
|
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Each value is the mean ± SEM. Means have different superscript letters indicate significant variation at (P ≤ 0.05), while the same letters indicate non significant variation
- Plasma glucose was significant increased in HFD group compared with control and these levels were significantly lowered in HFD+G than HFD group p ≤ 0.05. There were significant increases in G6pD activities in HSD and HSD+G groups p ≤ 0.05 than control, while giving Garcinia ameliorated these changes.
- Mesenteric, perirenal and epididymal adipose tissue weight were significantly increased in HFD and HSD compared with control group.
- The mesenteric, perirenal and epididymal fat-pad weights were reduced by 28%, 61% and 52% respectively in rats fed HFD+G than HFD rat (p < 0.05). While the mesenteric, perirenal and epididymal fat-pad weights were reduced by 31%, 35% and 37% respectively, in rats fed HSD+G than HSD rat. Garcinia treatment tended to decrease adipose tissues weight compared with HFD and HSD
- Effect of HFD, HSD and Garcinia treatments on renal catalase and both serum and renal MDA and NO levels in rats.